| Season | Team | League | GP | G | A | TP | PIM | Playoffs | GP | G | A | TP | PIM | |
| 2003-2004 | St. Mary's Prep | USHS-MI | - | - | - | - | - | | | ||||||
| 2004-2005 | St. Mary's Prep | USHS-MI | 23 | 2 | 8 | 10 | - | | | Playoffs | 6 | 2 | 5 | 7 | - |
| 2005-2006 | Des Moines Buccaneers | USHL | 48 | 1 | 14 | 15 | 68 | | | Playoffs | 11 | 2 | 5 | 7 | 8 |
| 2006-2007 | Des Moines Buccaneers | USHL | 55 | 18 | 27 | 45 | 71 | | | Playoffs | 8 | 0 | 6 | 6 | 10 |
| 2007-2008 | Michigan State Univ. | NCAA | 42 | 3 | 21 | 24 | 28 | | | ||||||
| 2008-2009 | Michigan State Univ. | NCAA | 38 | 2 | 12 | 14 | 32 | | | ||||||
| 2009-2010 | Michigan State Univ. | NCAA | 38 | 4 | 25 | 29 | 26 | | | ||||||
| Springfield Falcons | AHL | 8 | 0 | 3 | 3 | 2 | | | |||||||
| 2010-2011 | Edmonton Oilers | NHL | 35 | 1 | 4 | 5 | 10 | | | ||||||
| Oklahoma City Barons | AHL | 41 | 7 | 17 | 24 | 18 | | | Playoffs | 6 | 0 | 1 | 1 | 4 | |
| 2011-2012 | Edmonton Oilers | NHL | 73 | 2 | 23 | 25 | 26 | | | ||||||
| Oklahoma City Barons | AHL | 2 | 0 | 1 | 1 | 2 | | | |||||||
| USA | WC | 8 | 2 | 3 | 5 | 4 | | | |||||||
| 2012-2013 | Edmonton Oilers | NHL | 48 | 3 | 9 | 12 | 29 | | | ||||||
| USA | WC | 10 | 0 | 0 | 0 | 4 | | | |||||||
| 2013-2014 | Edmonton Oilers | NHL | 80 | 7 | 10 | 17 | 42 | | | ||||||
| USA | WC | 8 | 0 | 4 | 4 | 4 | | | |||||||
| 2014-2015 | Edmonton Oilers | NHL | 59 | 4 | 11 | 15 | 32 | | | ||||||
| Montréal Canadiens | NHL | 19 | 3 | 4 | 7 | 10 | | | Playoffs | 12 | 2 | 1 | 3 | 4 | |
| 2015-2016 | Montréal Canadiens | NHL | 51 | 5 | 11 | 16 | 16 | | | ||||||
| 2016-2017 | Montréal Canadiens | NHL | 80 | 8 | 20 | 28 | 22 | | | Playoffs | 6 | 1 | 0 | 1 | 2 |
| 2017-2018 | Montréal Canadiens | NHL | 82 | 12 | 30 | 42 | 28 | | | ||||||
| 2018-2019 | Montréal Canadiens | NHL | 82 | 13 | 33 | 46 | 28 | | | ||||||
| 2019-2020 | Montréal Canadiens | NHL | 71 | 11 | 29 | 40 | 26 | | | Playoffs | 10 | 2 | 1 | 3 | 6 |
| 2020-2021 | Montréal Canadiens | NHL | 55 | 12 | 30 | 42 | 20 | | | Playoffs | 20 | 0 | 6 | 6 | 6 |
| 2021-2022 | Montréal Canadiens | NHL | - | - | - | - | - | | |