| 1. | Sidney Crosby (C) | Pittsburgh Penguins | 79 | 36 | 84 | 120 | 1.52 | 60 | 10 |
| 2. | Alexander Ovechkin (LW/RW) | Washington Capitals | 82 | 46 | 46 | 92 | 1.12 | 52 | -19 |
| 3. | Jason Spezza (C) | Ottawa Senators | 67 | 34 | 53 | 87 | 1.30 | 45 | 19 |
| 4. | Yevgeni Malkin (C) | Pittsburgh Penguins | 78 | 33 | 52 | 85 | 1.09 | 80 | 2 |
| 5. | Thomas Vanek (LW/RW) | Buffalo Sabres | 82 | 43 | 41 | 84 | 1.02 | 40 | 47 |
| 6. | Michael Cammalleri (LW) | Los Angeles Kings | 81 | 34 | 46 | 80 | 0.99 | 48 | 5 |
| 7. | Paul Stastny (C) | Colorado Avalanche | 82 | 28 | 50 | 78 | 0.95 | 42 | 4 |
| 8. | Ilya Kovalchuk (LW) | Atlanta Thrashers | 82 | 42 | 34 | 76 | 0.93 | 66 | -2 |
| 9. | Alexander Syomin (LW) | Washington Capitals | 77 | 38 | 35 | 73 | 0.95 | 90 | -7 |
| 10. | Alexander Frolov (LW) | Los Angeles Kings | 82 | 35 | 36 | 71 | 0.87 | 34 | -8 |
| 11. | Eric Staal (C) | Carolina Hurricanes | 82 | 30 | 40 | 70 | 0.85 | 68 | -6 |
| 12. | Patrice Bergeron (C) | Boston Bruins | 77 | 22 | 48 | 70 | 0.91 | 26 | -28 |
| 13. | Jason Pominville (RW) | Buffalo Sabres | 82 | 34 | 34 | 68 | 0.83 | 30 | 25 |
| 14. | Milan Michálek (LW/RW) | San Jose Sharks | 78 | 26 | 40 | 66 | 0.85 | 36 | 17 |
| 15. | Derek Roy (C) | Buffalo Sabres | 75 | 21 | 42 | 63 | 0.84 | 60 | 37 |
| 16. | Zach Parise (LW/RW) | New Jersey Devils | 82 | 31 | 31 | 62 | 0.76 | 30 | -3 |
| 17. | Nathan Horton (RW) | Florida Panthers | 82 | 31 | 31 | 62 | 0.76 | 61 | 15 |
| 18. | Anze Kopitar (C/LW) | Los Angeles Kings | 72 | 20 | 41 | 61 | 0.85 | 24 | -12 |
| 19. | Ryan Getzlaf (C) | Anaheim Ducks | 82 | 25 | 33 | 58 | 0.71 | 66 | 17 |
| 20. | Marián Gáborík (RW) | Minnesota Wild | 48 | 30 | 27 | 57 | 1.19 | 40 | 12 |
| 21. | Rick Nash (LW) | Columbus Blue Jackets | 75 | 27 | 30 | 57 | 0.76 | 73 | -8 |
| 22. | Pierre-Marc Bouchard (C) | Minnesota Wild | 82 | 20 | 37 | 57 | 0.70 | 14 | 13 |
| 23. | Mikko Koivu (C) | Minnesota Wild | 82 | 20 | 34 | 54 | 0.66 | 58 | 6 |
| 24. | Ales Hemsky (RW) | Edmonton Oilers | 64 | 13 | 40 | 53 | 0.83 | 40 | -7 |
| 25. | Lee Stempniak (RW) | St. Louis Blues | 82 | 27 | 25 | 52 | 0.63 | 33 | -2 |
| 26. | Wojtek Wolski (LW/RW) | Colorado Avalanche | 76 | 22 | 28 | 50 | 0.66 | 14 | 2 |
| 27. | Stephen Weiss (C) | Florida Panthers | 74 | 20 | 28 | 48 | 0.65 | 28 | -1 |
| 28. | Michel Ouellet (RW) | Pittsburgh Penguins | 73 | 19 | 29 | 48 | 0.66 | 30 | -3 |
| 29. | Jussi Jokinen (W/C) | Dallas Stars | 82 | 14 | 34 | 48 | 0.59 | 18 | 8 |
| 30. | Tomas Plekanec (C) | Montréal Canadiens | 81 | 20 | 27 | 47 | 0.58 | 36 | 10 |
| 31. | Matthew Lombardi (C) | Calgary Flames | 81 | 20 | 26 | 46 | 0.57 | 48 | 10 |
| 32. | Brad Boyes (RW) | totals | 81 | 17 | 29 | 46 | 0.57 | 29 | -17 |
| Boston Bruins | Boston Bruins | 62 | 13 | 21 | 34 | 0.55 | 25 | -17 |
| St. Louis Blues | St. Louis Blues | 19 | 4 | 8 | 12 | 0.63 | 4 | 0 |
| 33. | Dustin Brown (RW/LW) | Los Angeles Kings | 81 | 17 | 29 | 46 | 0.57 | 54 | -21 |
| 34. | Dustin Penner (LW) | Anaheim Ducks | 82 | 29 | 16 | 45 | 0.55 | 58 | -2 |
| 35. | Corey Perry (RW/LW) | Anaheim Ducks | 82 | 17 | 27 | 44 | 0.54 | 55 | 12 |
| 36. | Jordan Staal (C/LW) | Pittsburgh Penguins | 81 | 29 | 13 | 42 | 0.52 | 24 | 16 |
| 37. | Travis Zajac (C/RW) | New Jersey Devils | 80 | 17 | 25 | 42 | 0.53 | 16 | 1 |
| 38. | Kyle Wellwood (C) | Toronto Maple Leafs | 48 | 12 | 30 | 42 | 0.88 | 0 | 3 |
| 39. | Petr Prucha (RW/LW) | New York Rangers | 79 | 22 | 18 | 40 | 0.51 | 30 | -7 |
| 40. | Scott Hartnell (LW) | Nashville Predators | 64 | 22 | 17 | 39 | 0.61 | 96 | 19 |
| 41. | Antoine Vermette (C) | Ottawa Senators | 77 | 19 | 20 | 39 | 0.51 | 52 | -2 |
| 42. | Jarret Stoll (C) | Edmonton Oilers | 51 | 13 | 26 | 39 | 0.76 | 48 | 2 |
| 43. | Matt Stajan (C) | Toronto Maple Leafs | 82 | 10 | 29 | 39 | 0.48 | 44 | 3 |
| 44. | Chris Higgins (LW) | Montréal Canadiens | 61 | 22 | 16 | 38 | 0.62 | 26 | -11 |
| 45. | Tuomo Ruutu (W/C) | Chicago Blackhawks | 71 | 17 | 21 | 38 | 0.54 | 95 | 4 |
| 46. | Alexander Radulov (RW) | Nashville Predators | 64 | 18 | 19 | 37 | 0.58 | 26 | 19 |
| 47. | Jeff Carter (C) | Philadelphia Flyers | 62 | 14 | 23 | 37 | 0.60 | 48 | -17 |
| 48. | Jay McClement (C/D) | St. Louis Blues | 81 | 8 | 28 | 36 | 0.44 | 55 | 3 |
| 49. | Alexander Steen (C) | Toronto Maple Leafs | 82 | 15 | 20 | 35 | 0.43 | 26 | 5 |
| 50. | Ryane Clowe (LW) | San Jose Sharks | 58 | 16 | 18 | 34 | 0.59 | 78 | 4 |
| 51. | Colby Armstrong (RW/LW) | Pittsburgh Penguins | 80 | 12 | 22 | 34 | 0.43 | 67 | 2 |
| 52. | Erik Christensen (C) | Pittsburgh Penguins | 61 | 18 | 15 | 33 | 0.54 | 26 | -3 |
| 53. | Patrick Eaves (RW/LW) | Ottawa Senators | 73 | 14 | 18 | 32 | 0.44 | 36 | 1 |
| 54. | Mike Richards (C) | Philadelphia Flyers | 59 | 10 | 22 | 32 | 0.54 | 52 | -12 |
| 55. | Nikolai Zherdev (LW/RW) | Columbus Blue Jackets | 71 | 10 | 22 | 32 | 0.45 | 26 | -19 |
| 56. | Steve Bernier (RW) | San Jose Sharks | 62 | 15 | 16 | 31 | 0.50 | 29 | 5 |
| 57. | Marek Svatos (RW) | Colorado Avalanche | 66 | 15 | 15 | 30 | 0.45 | 46 | 1 |
| 58. | Rostislav Olesz (LW/RW) | Florida Panthers | 75 | 11 | 19 | 30 | 0.40 | 28 | 2 |
| 59. | Guillaume Latendresse (LW/RW) | Montréal Canadiens | 80 | 16 | 13 | 29 | 0.36 | 47 | -20 |
| 60. | Phil Kessel (RW) | Boston Bruins | 70 | 11 | 18 | 29 | 0.41 | 12 | -12 |
| 61. | Boyd Gordon (C) | Washington Capitals | 71 | 7 | 22 | 29 | 0.41 | 14 | 10 |
| 62. | R.J. Umberger (C/W) | Philadelphia Flyers | 81 | 16 | 12 | 28 | 0.35 | 41 | -32 |
| 63. | Joffrey Lupul (RW) | Edmonton Oilers | 81 | 16 | 12 | 28 | 0.35 | 45 | -29 |
| 64. | Joe Pavelski (C/RW) | San Jose Sharks | 46 | 14 | 14 | 28 | 0.61 | 18 | 4 |
| 65. | Ryan Craig (C/LW) | Tampa Bay Lightning | 72 | 14 | 13 | 27 | 0.38 | 55 | 11 |
| 66. | Drew Stafford (RW) | Buffalo Sabres | 41 | 13 | 14 | 27 | 0.66 | 33 | 5 |
| 67. | Dan Fritsche (C/W) | Columbus Blue Jackets | 59 | 12 | 15 | 27 | 0.46 | 35 | 3 |
| 68. | Jiri Hudler (W/C) | Detroit Red Wings | 76 | 15 | 10 | 25 | 0.33 | 36 | 16 |
| 69. | Brandon Bochenski (RW/LW) | totals | 41 | 13 | 11 | 24 | 0.59 | 16 | 1 |
| Chicago Blackhawks | Chicago Blackhawks | 10 | 2 | 0 | 2 | 0.20 | 2 | -2 |
| Boston Bruins | Boston Bruins | 31 | 11 | 11 | 22 | 0.71 | 14 | 3 |
| 70. | Maxime Talbot (C) | Pittsburgh Penguins | 75 | 13 | 11 | 24 | 0.32 | 53 | -2 |
| 71. | David Backes (RW/C) | St. Louis Blues | 49 | 10 | 13 | 23 | 0.47 | 37 | 6 |
| 72. | Brad Richardson (RW/C) | Colorado Avalanche | 73 | 14 | 8 | 22 | 0.30 | 28 | 4 |
| 73. | Paul Gaustad (C) | Buffalo Sabres | 54 | 9 | 13 | 22 | 0.41 | 74 | 11 |
| 74. | Andrew Ladd (LW) | Carolina Hurricanes | 65 | 11 | 10 | 21 | 0.32 | 46 | 1 |
| 75. | Travis Moen (LW/RW) | Anaheim Ducks | 82 | 11 | 10 | 21 | 0.26 | 101 | -4 |
| 76. | Gilbert Brulé (C/RW) | Columbus Blue Jackets | 78 | 9 | 10 | 19 | 0.24 | 28 | -21 |
| 77. | Loui Eriksson (LW) | Dallas Stars | 59 | 6 | 13 | 19 | 0.32 | 18 | -3 |
| 78. | Jiri Novotny (C) | totals | 68 | 6 | 13 | 19 | 0.28 | 28 | -4 |
| Buffalo Sabres | Buffalo Sabres | 50 | 6 | 7 | 13 | 0.26 | 26 | -2 |
| Washington Capitals | Washington Capitals | 18 | 0 | 6 | 6 | 0.33 | 2 | -2 |
| 79. | Patrick O'Sullivan (C) | Los Angeles Kings | 44 | 5 | 14 | 19 | 0.43 | 14 | -6 |
| 80. | Chuck Kobasew (RW) | totals | 50 | 5 | 14 | 19 | 0.38 | 62 | 1 |
| Calgary Flames | Calgary Flames | 40 | 4 | 13 | 17 | 0.43 | 37 | 7 |
| Boston Bruins | Boston Bruins | 10 | 1 | 1 | 2 | 0.20 | 25 | -6 |
| 81. | Jim Slater (C) | Atlanta Thrashers | 74 | 5 | 14 | 19 | 0.26 | 62 | 8 |
| 82. | Fredrik Sjöström (LW) | Arizona Coyotes | 78 | 9 | 9 | 18 | 0.23 | 48 | -11 |
| 83. | Brooks Laich (C/LW) | Washington Capitals | 73 | 8 | 10 | 18 | 0.25 | 29 | -2 |
| 84. | Alexander Svitov (C) | Columbus Blue Jackets | 76 | 7 | 11 | 18 | 0.24 | 145 | -10 |
| 85. | Chad LaRose (RW/LW) | Carolina Hurricanes | 80 | 6 | 12 | 18 | 0.23 | 10 | -2 |
| 86. | Valtteri Filppula (C/LW) | Detroit Red Wings | 73 | 10 | 7 | 17 | 0.23 | 20 | 8 |
| 87. | Brian Sutherby (C) | Washington Capitals | 69 | 7 | 10 | 17 | 0.25 | 78 | -9 |
| 88. | Scottie Upshall (LW/RW) | totals | 32 | 8 | 8 | 16 | 0.50 | 26 | 3 |
| Nashville Predators | Nashville Predators | 14 | 2 | 1 | 3 | 0.21 | 18 | -1 |
| Philadelphia Flyers | Philadelphia Flyers | 18 | 6 | 7 | 13 | 0.72 | 8 | 4 |
| 89. | Ryan Kesler (C) | Vancouver Canucks | 48 | 6 | 10 | 16 | 0.33 | 40 | 1 |
| 90. | Patrick Thoresen (W/C) | Edmonton Oilers | 68 | 4 | 12 | 16 | 0.24 | 52 | -1 |
| 91. | Alexander Perezhogin (LW/RW) | Montréal Canadiens | 61 | 6 | 9 | 15 | 0.25 | 48 | 11 |
| 92. | Bill Thomas (RW) | Arizona Coyotes | 24 | 8 | 6 | 14 | 0.58 | 2 | -6 |
| 93. | Stanislav Chistov (LW) | totals | 61 | 5 | 8 | 13 | 0.21 | 36 | -8 |
| Anaheim Ducks | Anaheim Ducks | 1 | 0 | 0 | 0 | 0.00 | 0 | 0 |
| Boston Bruins | Boston Bruins | 60 | 5 | 8 | 13 | 0.22 | 36 | -8 |
| 94. | Marcel Goc (C) | San Jose Sharks | 78 | 5 | 8 | 13 | 0.17 | 24 | -2 |
| 95. | Stefan Ruzicka (RW) | Philadelphia Flyers | 40 | 3 | 10 | 13 | 0.33 | 18 | -6 |
| 96. | Ryan Potulny (C) | Philadelphia Flyers | 35 | 7 | 5 | 12 | 0.34 | 22 | 1 |
| 97. | Maxim Lapierre (C) | Montréal Canadiens | 46 | 6 | 6 | 12 | 0.26 | 24 | -7 |
| 98. | Ben Eager (LW) | Philadelphia Flyers | 63 | 6 | 5 | 11 | 0.17 | 233 | -13 |
| 99. | Marc-Antoine Pouliot (C/RW) | Edmonton Oilers | 46 | 4 | 7 | 11 | 0.24 | 18 | -2 |
| 100. | Daniel Paille (LW) | Buffalo Sabres | 29 | 3 | 8 | 11 | 0.38 | 18 | 5 |