| 1. | J.T. Miller (C/W) | Vancouver Canucks | 94 | 40 | 75 | 115 | 1.22 | 66 | 37 |
| 2. | Auston Matthews (C/LW) | Toronto Maple Leafs | 86 | 70 | 41 | 111 | 1.29 | 22 | 33 |
| 3. | Matthew Tkachuk (LW/RW) | Florida Panthers | 104 | 32 | 78 | 110 | 1.06 | 119 | 19 |
| 4. | Quinn Hughes (D) | Vancouver Canucks | 95 | 17 | 85 | 102 | 1.07 | 44 | 39 |
| 5. | Vincent Trocheck (C) | New York Rangers | 98 | 33 | 64 | 97 | 0.99 | 65 | 19 |
| 6. | Jason Robertson (LW/RW) | Dallas Stars | 101 | 35 | 61 | 96 | 0.95 | 22 | 17 |
| 7. | Chris Kreider (LW/RW) | New York Rangers | 98 | 47 | 40 | 87 | 0.89 | 32 | 16 |
| 8. | Jake Guentzel (LW) | totals | 78 | 34 | 52 | 86 | 1.10 | 38 | 29 |
| Pittsburgh Penguins | Pittsburgh Penguins | 50 | 22 | 30 | 52 | 1.04 | 14 | 9 |
| Carolina Hurricanes | Carolina Hurricanes | 28 | 12 | 22 | 34 | 1.21 | 24 | 20 |
| 9. | Brock Boeser (RW/LW) | Vancouver Canucks | 93 | 47 | 38 | 85 | 0.91 | 22 | 25 |
| 10. | Adam Fox (D) | New York Rangers | 88 | 17 | 64 | 81 | 0.92 | 44 | 26 |
| 11. | Clayton Keller (RW/LW) | Arizona Coyotes | 78 | 33 | 43 | 76 | 0.97 | 32 | -20 |
| 12. | Jack Eichel (C) | Vegas Golden Knights | 70 | 34 | 41 | 75 | 1.07 | 27 | 4 |
| 13. | Brady Tkachuk (LW) | Ottawa Senators | 81 | 37 | 37 | 74 | 0.91 | 134 | 1 |
| 14. | Jack Hughes (C/LW) | New Jersey Devils | 62 | 27 | 47 | 74 | 1.19 | 12 | -12 |
| 15. | Brock Nelson (C/LW) | New York Islanders | 87 | 36 | 37 | 73 | 0.84 | 38 | -7 |
| 16. | Joe Pavelski (C/RW) | Dallas Stars | 101 | 28 | 43 | 71 | 0.70 | 22 | 7 |
| 17. | Dylan Larkin (C/LW) | Detroit Red Wings | 68 | 33 | 36 | 69 | 1.01 | 39 | 5 |
| 18. | Matt Boldy (LW/RW) | Minnesota Wild | 75 | 29 | 40 | 69 | 0.92 | 48 | 5 |
| 19. | Alex DeBrincat (RW/LW) | Detroit Red Wings | 82 | 27 | 40 | 67 | 0.82 | 34 | 1 |
| 20. | Kyle Connor (LW) | Winnipeg Jets | 70 | 37 | 29 | 66 | 0.94 | 10 | -8 |
| 21. | Casey Mittelstadt (C/LW) | totals | 91 | 21 | 45 | 66 | 0.73 | 34 | 10 |
| Buffalo Sabres | Buffalo Sabres | 62 | 14 | 33 | 47 | 0.76 | 28 | 12 |
| Colorado Avalanche | Colorado Avalanche | 29 | 7 | 12 | 19 | 0.66 | 6 | -2 |
| 22. | Cole Caufield (LW/RW) | Montréal Canadiens | 82 | 28 | 37 | 65 | 0.79 | 16 | -4 |
| 23. | Charlie Coyle (C/RW) | Boston Bruins | 95 | 26 | 39 | 65 | 0.68 | 50 | -2 |
| 24. | Nick Schmaltz (C/RW) | Arizona Coyotes | 79 | 22 | 39 | 61 | 0.77 | 10 | -16 |
| 25. | Frank Vatrano (RW/LW) | Anaheim Ducks | 82 | 37 | 23 | 60 | 0.73 | 85 | -20 |
| 26. | Johnny Gaudreau (LW) | Columbus Blue Jackets | 81 | 12 | 48 | 60 | 0.74 | 22 | -27 |
| 27. | Alex Tuch (RW) | Buffalo Sabres | 75 | 22 | 37 | 59 | 0.79 | 54 | 9 |
| 28. | Trevor Moore (W/C) | Los Angeles Kings | 87 | 32 | 26 | 58 | 0.67 | 32 | 10 |
| 29. | Kyle Palmieri (RW) | New York Islanders | 87 | 31 | 26 | 57 | 0.66 | 38 | -17 |
| 30. | Zach Werenski (D) | Columbus Blue Jackets | 70 | 11 | 46 | 57 | 0.81 | 22 | 0 |
| 31. | Tage Thompson (C/W) | Buffalo Sabres | 71 | 29 | 27 | 56 | 0.79 | 43 | -1 |
| 32. | Bryan Rust (RW/LW) | Pittsburgh Penguins | 62 | 28 | 28 | 56 | 0.90 | 20 | 10 |
| 33. | Brady Skjei (D) | Carolina Hurricanes | 91 | 14 | 42 | 56 | 0.62 | 46 | 20 |
| 34. | Shayne Gostisbehere (D) | Detroit Red Wings | 81 | 10 | 46 | 56 | 0.69 | 16 | -16 |
| 35. | Blake Coleman (LW/RW) | Calgary Flames | 78 | 30 | 24 | 54 | 0.69 | 76 | 19 |
| 36. | Troy Terry (W/C) | Anaheim Ducks | 76 | 20 | 34 | 54 | 0.71 | 24 | -10 |
| 37. | John Carlson (D) | Washington Capitals | 86 | 11 | 43 | 54 | 0.63 | 42 | -8 |
| 38. | Charlie McAvoy (D) | Boston Bruins | 87 | 13 | 40 | 53 | 0.61 | 106 | 0 |
| 39. | Conor Garland (RW/LW) | Vancouver Canucks | 95 | 23 | 29 | 52 | 0.55 | 37 | 19 |
| 40. | Noah Hanifin (D) | totals | 87 | 15 | 37 | 52 | 0.60 | 24 | 17 |
| Calgary Flames | Calgary Flames | 61 | 11 | 24 | 35 | 0.57 | 22 | 13 |
| Vegas Golden Knights | Vegas Golden Knights | 26 | 4 | 13 | 17 | 0.65 | 2 | 4 |
| 41. | Joel Farabee (LW/RW) | Philadelphia Flyers | 82 | 22 | 28 | 50 | 0.61 | 37 | -13 |
| 42. | J.T. Compher (W/C) | Detroit Red Wings | 77 | 19 | 29 | 48 | 0.62 | 34 | -5 |
| 43. | Patrick Kane (RW/LW) | Detroit Red Wings | 50 | 20 | 27 | 47 | 0.94 | 16 | -5 |
| 44. | Luke Hughes (D) | New Jersey Devils | 82 | 9 | 38 | 47 | 0.57 | 28 | -25 |
| 45. | Brock Faber (D) | Minnesota Wild | 82 | 8 | 39 | 47 | 0.57 | 26 | -1 |
| 46. | Nick Bjugstad (C/RW) | Arizona Coyotes | 76 | 22 | 23 | 45 | 0.59 | 59 | 11 |
| 47. | Ryan Hartman (RW/C) | Minnesota Wild | 74 | 21 | 24 | 45 | 0.61 | 72 | 4 |
| 48. | Trent Frederic (C/W) | Boston Bruins | 95 | 21 | 24 | 45 | 0.47 | 89 | 14 |
| 49. | Tommy Novak (C) | Nashville Predators | 77 | 18 | 27 | 45 | 0.58 | 8 | -4 |
| 50. | Logan Cooley (C/LW) | Arizona Coyotes | 82 | 20 | 24 | 44 | 0.54 | 18 | -13 |
| 51. | Ross Colton (C/W) | Colorado Avalanche | 91 | 18 | 26 | 44 | 0.48 | 63 | -6 |
| 52. | James van Riemsdyk (LW/RW) | Boston Bruins | 82 | 12 | 31 | 43 | 0.52 | 20 | 6 |
| 53. | Brandon Saad (LW/RW) | St. Louis Blues | 82 | 26 | 16 | 42 | 0.51 | 20 | -4 |
| 54. | Anders Lee (LW) | New York Islanders | 86 | 21 | 20 | 41 | 0.48 | 74 | -2 |
| 55. | Stefan Noesen (RW/LW) | Carolina Hurricanes | 92 | 18 | 23 | 41 | 0.45 | 54 | 14 |
| 56. | Dakota Joshua (LW/C) | Vancouver Canucks | 76 | 22 | 18 | 40 | 0.53 | 70 | 20 |
| 57. | Jaccob Slavin (D) | Carolina Hurricanes | 92 | 7 | 33 | 40 | 0.43 | 10 | 26 |
| 58. | Jack Roslovic (C/RW) | totals | 75 | 11 | 28 | 39 | 0.52 | 22 | -10 |
| Columbus Blue Jackets | Columbus Blue Jackets | 40 | 6 | 17 | 23 | 0.58 | 14 | -9 |
| New York Rangers | New York Rangers | 35 | 5 | 11 | 16 | 0.46 | 8 | -1 |
| 59. | Cam Fowler (D) | Anaheim Ducks | 81 | 5 | 34 | 39 | 0.48 | 24 | -36 |
| 60. | Torey Krug (D) | St. Louis Blues | 77 | 4 | 35 | 39 | 0.51 | 32 | -31 |
| 61. | Matthew Knies (LW/RW) | Toronto Maple Leafs | 87 | 17 | 21 | 38 | 0.44 | 47 | 8 |
| 62. | Mason Appleton (C/RW) | Winnipeg Jets | 87 | 14 | 24 | 38 | 0.44 | 32 | 12 |
| 63. | Jake Sanderson (D) | Ottawa Senators | 79 | 10 | 28 | 38 | 0.48 | 23 | 8 |
| 64. | Nick Foligno (LW/RW) | Chicago Blackhawks | 74 | 17 | 20 | 37 | 0.50 | 57 | -29 |
| 65. | Matty Beniers (C) | Seattle Kraken | 77 | 15 | 22 | 37 | 0.48 | 20 | -11 |
| 66. | Jason Zucker (LW/RW) | totals | 75 | 15 | 20 | 35 | 0.47 | 83 | -5 |
| Arizona Coyotes | Arizona Coyotes | 51 | 9 | 16 | 25 | 0.49 | 58 | -5 |
| Nashville Predators | Nashville Predators | 24 | 6 | 4 | 10 | 0.42 | 25 | 0 |
| 67. | K'Andre Miller (D) | New York Rangers | 96 | 9 | 25 | 34 | 0.35 | 57 | 7 |
| 68. | Neal Pionk (D) | Winnipeg Jets | 87 | 5 | 29 | 34 | 0.39 | 67 | 7 |
| 69. | Drew O'Connor (LW/RW) | Pittsburgh Penguins | 79 | 16 | 17 | 33 | 0.42 | 20 | 14 |
| 70. | Andrew Copp (C/LW) | Detroit Red Wings | 79 | 13 | 20 | 33 | 0.42 | 26 | -2 |
| 71. | Ryan McDonagh (D) | Nashville Predators | 80 | 3 | 30 | 33 | 0.41 | 37 | 18 |
| 72. | Jack Drury (C/LW) | Carolina Hurricanes | 85 | 9 | 23 | 32 | 0.38 | 35 | 11 |
| 73. | Tyler Johnson (C/RW) | Chicago Blackhawks | 67 | 17 | 14 | 31 | 0.46 | 26 | -35 |
| 74. | Seth Jones (D) | Chicago Blackhawks | 67 | 8 | 23 | 31 | 0.46 | 34 | -15 |
| 75. | Josh Norris (C/LW) | Ottawa Senators | 50 | 16 | 14 | 30 | 0.60 | 22 | -6 |
| 76. | Ryan Donato (C/W) | Chicago Blackhawks | 78 | 12 | 18 | 30 | 0.38 | 26 | -14 |
| 77. | Cam York (D) | Philadelphia Flyers | 82 | 10 | 20 | 30 | 0.37 | 44 | -13 |
| 78. | Justin Faulk (D) | St. Louis Blues | 60 | 2 | 28 | 30 | 0.50 | 39 | -2 |
| 79. | Jimmy Vesey (LW/RW) | New York Rangers | 92 | 14 | 15 | 29 | 0.32 | 22 | -3 |
| 80. | Kevin Hayes (C/LW) | St. Louis Blues | 79 | 13 | 16 | 29 | 0.37 | 12 | 0 |
| 81. | Miles Wood (LW/RW) | Colorado Avalanche | 85 | 12 | 17 | 29 | 0.34 | 88 | -4 |
| 82. | Jake McCabe (D) | Toronto Maple Leafs | 80 | 9 | 20 | 29 | 0.36 | 60 | 20 |
| 83. | Jacob Trouba (D) | New York Rangers | 85 | 4 | 25 | 29 | 0.34 | 95 | -4 |
| 84. | Cam Atkinson (RW/LW) | Philadelphia Flyers | 70 | 13 | 15 | 28 | 0.40 | 27 | -22 |
| 85. | Kiefer Sherwood (W/C) | Nashville Predators | 74 | 11 | 17 | 28 | 0.38 | 41 | 15 |
| 86. | Ryan Poehling (C/LW) | Philadelphia Flyers | 77 | 11 | 17 | 28 | 0.36 | 6 | -11 |
| 87. | Alex Iafallo (LW/C) | Winnipeg Jets | 87 | 11 | 17 | 28 | 0.32 | 6 | 13 |
| 88. | Jordan Greenway (W/C) | Buffalo Sabres | 67 | 10 | 18 | 28 | 0.42 | 64 | 11 |
| 89. | Nick Leddy (D) | St. Louis Blues | 82 | 3 | 25 | 28 | 0.34 | 14 | 14 |
| 90. | Nick Robertson (LW/RW) | Toronto Maple Leafs | 62 | 14 | 13 | 27 | 0.44 | 4 | 2 |
| 91. | Shane Pinto (C) | Ottawa Senators | 41 | 9 | 18 | 27 | 0.66 | 14 | 9 |
| 92. | Matt Roy (D) | Los Angeles Kings | 86 | 5 | 22 | 27 | 0.31 | 44 | 22 |
| 93. | T.J. Oshie (RW) | Washington Capitals | 56 | 12 | 14 | 26 | 0.46 | 48 | -8 |
| 94. | Mike Reilly (D) | totals | 66 | 7 | 19 | 26 | 0.39 | 30 | -4 |
| Florida Panthers | Florida Panthers | 2 | 0 | 0 | 0 | 0.00 | 2 | -2 |
| New York Islanders | New York Islanders | 64 | 7 | 19 | 26 | 0.41 | 28 | -2 |
| 95. | Alex Laferriere (RW/LW) | Los Angeles Kings | 86 | 13 | 12 | 25 | 0.29 | 46 | -14 |
| 96. | Michael Eyssimont (C/LW) | Tampa Bay Lightning | 86 | 11 | 14 | 25 | 0.29 | 106 | 5 |
| 97. | Paul Cotter (C/W) | Vegas Golden Knights | 76 | 7 | 18 | 25 | 0.33 | 41 | -11 |
| 98. | Kevin Shattenkirk (D) | Boston Bruins | 67 | 6 | 19 | 25 | 0.37 | 18 | -3 |
| 99. | John Marino (D) | New Jersey Devils | 75 | 4 | 21 | 25 | 0.33 | 41 | -6 |
| 100. | Will Borgen (D) | Seattle Kraken | 82 | 3 | 22 | 25 | 0.30 | 65 | -5 |