| 1. | Patrick Kane (RW/LW) | London Knights | 74 | 72 | 104 | 176 | 2.38 | 68 | 44 |
| 2. | Tyler Donati (RW/LW) | Belleville Bulls | 81 | 60 | 95 | 155 | 1.91 | 56 | 13 |
| 3. | John Tavares (C/LW) | Oshawa Generals | 76 | 79 | 74 | 153 | 2.01 | 66 | 21 |
| 4. | Sergei Kostitsyn (RW/LW) | London Knights | 75 | 49 | 103 | 152 | 2.03 | 115 | 36 |
| 5. | Sam Gagner (C/RW) | London Knights | 69 | 42 | 105 | 147 | 2.13 | 58 | 33 |
| 6. | Evan Brophey (C/LW) | Plymouth Whalers | 88 | 45 | 85 | 130 | 1.48 | 117 | 47 |
| 7. | Justin Donati (C) | totals | 82 | 61 | 58 | 119 | 1.45 | 36 | 14 |
| Brampton Steelheads | Brampton Steelheads | 35 | 26 | 30 | 56 | 1.60 | 24 | -3 |
| Sudbury Wolves | Sudbury Wolves | 47 | 35 | 28 | 63 | 1.34 | 12 | 17 |
| 8. | Nick Foligno (LW/RW) | Sudbury Wolves | 87 | 43 | 74 | 117 | 1.34 | 171 | 27 |
| 9. | Bryan Little (C) | Barrie Colts | 65 | 45 | 71 | 116 | 1.78 | 85 | 34 |
| 10. | Brett MacLean (RW) | Oshawa Generals | 75 | 53 | 62 | 115 | 1.53 | 52 | 7 |
| 11. | Steve Downie (RW) | totals | 54 | 43 | 71 | 114 | 2.11 | 139 | 25 |
| Peterborough Petes | Peterborough Petes | 28 | 23 | 36 | 59 | 2.11 | 92 | 13 |
| Kitchener Rangers | Kitchener Rangers | 26 | 20 | 35 | 55 | 2.12 | 47 | 12 |
| 12. | Dustin Jeffrey (C) | Soo Greyhounds | 81 | 40 | 70 | 110 | 1.36 | 51 | 8 |
| 13. | Dan Ryder (C) | totals | 77 | 48 | 61 | 109 | 1.42 | 35 | 45 |
| Peterborough Petes | Peterborough Petes | 29 | 24 | 35 | 59 | 2.03 | 21 | 19 |
| Plymouth Whalers | Plymouth Whalers | 48 | 24 | 26 | 50 | 1.04 | 14 | 26 |
| 14. | Bobby Ryan (RW/LW) | Owen Sound Attack | 67 | 44 | 60 | 104 | 1.55 | 65 | -10 |
| 15. | Cal Clutterbuck (RW) | Oshawa Generals | 74 | 43 | 59 | 102 | 1.38 | 174 | 8 |
| 16. | Adam Perry (LW) | London Knights | 80 | 47 | 54 | 101 | 1.26 | 91 | 19 |
| 17. | Bobby Hughes (C) | Kingston Frontenacs | 64 | 40 | 59 | 99 | 1.55 | 76 | -4 |
| 18. | Steven Stamkos (C/W) | Sarnia Sting | 67 | 45 | 53 | 98 | 1.46 | 56 | 10 |
| 19. | Hunter Tremblay (LW) | Barrie Colts | 72 | 40 | 57 | 97 | 1.35 | 60 | 29 |
| 20. | Tyler Doig (C) | totals | 76 | 32 | 65 | 97 | 1.28 | 63 | 36 |
| Guelph Storm | Guelph Storm | 36 | 20 | 29 | 49 | 1.36 | 35 | 13 |
| Belleville Bulls | Belleville Bulls | 40 | 12 | 36 | 48 | 1.20 | 28 | 23 |
| 21. | David Meckler (C) | London Knights | 83 | 53 | 42 | 95 | 1.14 | 73 | 4 |
| 22. | Jamie McGinn (LW) | Ottawa 67's | 73 | 51 | 44 | 95 | 1.30 | 51 | -7 |
| 23. | Michael Swift (C/LW) | Mississauga IceDogs | 72 | 34 | 60 | 94 | 1.31 | 82 | 29 |
| 24. | Chris Lawrence (LW/C) | Mississauga IceDogs | 69 | 50 | 42 | 92 | 1.33 | 127 | 23 |
| 25. | Shawn Matthias (LW) | Belleville Bulls | 79 | 51 | 40 | 91 | 1.15 | 71 | 18 |
| 26. | James Neal (LW/RW) | Plymouth Whalers | 65 | 40 | 50 | 90 | 1.38 | 148 | 35 |
| 27. | Tom Pyatt (C) | Saginaw Spirit | 64 | 46 | 43 | 89 | 1.39 | 18 | 35 |
| 28. | Chris Stewart (RW/LW) | Kingston Frontenacs | 66 | 38 | 50 | 88 | 1.33 | 114 | -9 |
| 29. | Dan Collins (RW) | Plymouth Whalers | 86 | 35 | 53 | 88 | 1.02 | 117 | 33 |
| 30. | Cody Thornton (RW) | Soo Greyhounds | 81 | 39 | 48 | 87 | 1.07 | 145 | 7 |
| 31. | Scott Tregunna (RW) | Owen Sound Attack | 72 | 34 | 53 | 87 | 1.21 | 30 | -1 |
| 32. | Logan Couture (C/LW)  | Ottawa 67's | 59 | 27 | 59 | 86 | 1.46 | 28 | -2 |
| 33. | Dale Mitchell (RW) | Oshawa Generals | 76 | 44 | 41 | 85 | 1.12 | 93 | -4 |
| 34. | Rich Clune (LW) | Barrie Colts | 75 | 35 | 50 | 85 | 1.13 | 159 | 19 |
| 35. | Harrison Reed (RW/C) | Sarnia Sting | 71 | 29 | 56 | 85 | 1.20 | 38 | -3 |
| 36. | Chris Terry (LW/RW) | Plymouth Whalers | 88 | 30 | 54 | 84 | 0.95 | 119 | 26 |
| 37. | John Hughes (C/RW) | totals | 66 | 25 | 59 | 84 | 1.27 | 44 | -20 |
| Belleville Bulls | Belleville Bulls | 14 | 3 | 17 | 20 | 1.43 | 8 | 3 |
| Brampton Battalion | Brampton Battalion | 52 | 22 | 42 | 64 | 1.23 | 36 | -23 |
| 38. | Jan Mursak (C/RW) | Saginaw Spirit | 68 | 28 | 55 | 83 | 1.22 | 60 | 27 |
| 39. | Matt Beleskey (LW) | Belleville Bulls | 81 | 31 | 51 | 82 | 1.01 | 142 | 7 |
| 40. | Tom Sestito (LW) | Plymouth Whalers | 79 | 53 | 28 | 81 | 1.03 | 192 | 11 |
| 41. | Stefan Legein (RW) | Mississauga IceDogs | 69 | 46 | 34 | 80 | 1.16 | 115 | 31 |
| 42. | Jadran Beljo (LW) | Mississauga IceDogs | 68 | 36 | 44 | 80 | 1.18 | 75 | 29 |
| 43. | Drew Doughty (D) | Guelph Storm | 71 | 23 | 56 | 79 | 1.11 | 84 | 5 |
| 44. | Ryan Wilson (D) | Sarnia Sting | 72 | 18 | 61 | 79 | 1.10 | 150 | -2 |
| 45. | Trevor Kell (RW) | Sarnia Sting | 70 | 41 | 37 | 78 | 1.11 | 84 | 6 |
| 46. | Jonathan D'Aversa (D) | Sudbury Wolves | 88 | 16 | 62 | 78 | 0.89 | 69 | 22 |
| 47. | Jordan Owens (LW) | Mississauga IceDogs | 65 | 33 | 44 | 77 | 1.18 | 57 | 17 |
| 48. | Trevor Lewis (C/RW) | Owen Sound Attack | 66 | 30 | 46 | 76 | 1.15 | 51 | -18 |
| 49. | Peder Skinner (C) | Kingston Frontenacs | 65 | 29 | 47 | 76 | 1.17 | 4 | -8 |
| 50. | Matt Caria (C) | Brampton Steelheads | 59 | 33 | 42 | 75 | 1.27 | 114 | 0 |
| 51. | Cory Emmerton (C) | Kingston Frontenacs | 45 | 34 | 39 | 73 | 1.62 | 24 | -19 |
| 52. | Tomas Pospisil (RW) | Sarnia Sting | 59 | 30 | 43 | 73 | 1.24 | 42 | -2 |
| 53. | Kevin Baker (C) | Sudbury Wolves | 85 | 29 | 44 | 73 | 0.86 | 22 | -8 |
| 54. | Tyler Haskins (C/RW) | Saginaw Spirit | 71 | 12 | 61 | 73 | 1.03 | 100 | 8 |
| 55. | Ryan McDonough (C) | Saginaw Spirit | 72 | 34 | 38 | 72 | 1.00 | 67 | 6 |
| 56. | Matt Halischuk (RW) | Kitchener Rangers | 76 | 37 | 34 | 71 | 0.93 | 30 | 11 |
| 57. | Josh Godfrey (D) | Soo Greyhounds | 81 | 33 | 38 | 71 | 0.88 | 98 | -5 |
| 58. | Rob Drummond (C) | London Knights | 68 | 24 | 47 | 71 | 1.04 | 55 | 11 |
| 59. | Justin Azevedo (C/RW) | Kitchener Rangers | 59 | 21 | 50 | 71 | 1.20 | 64 | 9 |
| 60. | Bryan Cameron (C/RW) | Belleville Bulls | 75 | 37 | 33 | 70 | 0.93 | 65 | -3 |
| 61. | Zack Torquato (C) | totals | 65 | 30 | 39 | 69 | 1.06 | 93 | -24 |
| Saginaw Spirit | Saginaw Spirit | 22 | 10 | 13 | 23 | 1.05 | 24 | -1 |
| Erie Otters | Erie Otters | 43 | 20 | 26 | 46 | 1.07 | 69 | -23 |
| 62. | P.K. Subban (D) | Belleville Bulls | 83 | 20 | 49 | 69 | 0.83 | 115 | 23 |
| 63. | Michael Del Zotto (D) | Oshawa Generals | 73 | 13 | 56 | 69 | 0.95 | 92 | -6 |
| 64. | Luca Caputi (LW) | Mississauga IceDogs | 73 | 29 | 39 | 68 | 0.93 | 66 | 23 |
| 65. | Luke Lynes (C) | Brampton Battalion | 72 | 36 | 31 | 67 | 0.93 | 70 | -16 |
| 66. | Craig Voakes (LW) | totals | 70 | 23 | 44 | 67 | 0.96 | 54 | -34 |
| Windsor Spitfires | Windsor Spitfires | 39 | 9 | 26 | 35 | 0.90 | 30 | -17 |
| Sarnia Sting | Sarnia Sting | 31 | 14 | 18 | 32 | 1.03 | 24 | -17 |
| 67. | Jamie Arniel (C/RW) | Guelph Storm | 72 | 33 | 33 | 66 | 0.92 | 51 | 6 |
| 68. | Justin DiBenedetto (C/LW) | Sarnia Sting | 62 | 30 | 36 | 66 | 1.06 | 50 | 17 |
| 69. | Rafael Rotter (RW) | Guelph Storm | 65 | 17 | 49 | 66 | 1.02 | 98 | 8 |
| 70. | Jakub Kindl (D) | Kitchener Rangers | 63 | 13 | 53 | 66 | 1.05 | 150 | 20 |
| 71. | Jared Boll (RW) | Plymouth Whalers | 86 | 34 | 31 | 65 | 0.76 | 264 | 24 |
| 72. | Sean O'Connor (RW) | totals | 68 | 24 | 41 | 65 | 0.96 | 48 | 14 |
| Erie Otters | Erie Otters | 20 | 8 | 17 | 25 | 1.25 | 27 | -4 |
| Plymouth Whalers | Plymouth Whalers | 48 | 16 | 24 | 40 | 0.83 | 21 | 18 |
| 73. | Matt Auffrey (RW/LW) | totals | 70 | 31 | 33 | 64 | 0.91 | 124 | -8 |
| Kitchener Rangers | Kitchener Rangers | 7 | 3 | 1 | 4 | 0.57 | 16 | -2 |
| Brampton Battalion | Brampton Battalion | 27 | 11 | 13 | 24 | 0.89 | 63 | -14 |
| Kingston Frontenacs | Kingston Frontenacs | 36 | 17 | 19 | 36 | 1.00 | 45 | 8 |
| 74. | Nick Spaling (C/LW) | Kitchener Rangers | 70 | 25 | 39 | 64 | 0.91 | 45 | 23 |
| 75. | Patrick McNeill (D) | Saginaw Spirit | 64 | 25 | 38 | 63 | 0.98 | 55 | 7 |
| 76. | Victor Oreskovich (RW) | Kitchener Rangers | 67 | 30 | 32 | 62 | 0.93 | 52 | 11 |
| 77. | Brad Snetsinger (LW) | Windsor Spitfires | 63 | 29 | 33 | 62 | 0.98 | 86 | -31 |
| 78. | Howie Martin (C) | totals | 73 | 27 | 35 | 62 | 0.85 | 76 | -2 |
| Brampton Battalion | Brampton Battalion | 42 | 15 | 21 | 36 | 0.86 | 46 | 5 |
| Owen Sound Attack | Owen Sound Attack | 31 | 12 | 14 | 26 | 0.84 | 30 | -7 |
| 79. | Mike McLean (LW) | Guelph Storm | 71 | 29 | 32 | 61 | 0.86 | 28 | 4 |
| 80. | Josh Bailey (RW/C) | totals | 69 | 22 | 39 | 61 | 0.88 | 24 | -25 |
| Owen Sound Attack | Owen Sound Attack | 27 | 11 | 15 | 26 | 0.96 | 8 | -1 |
| Windsor Spitfires | Windsor Spitfires | 42 | 11 | 24 | 35 | 0.83 | 16 | -24 |
| 81. | Matt Kang (LW) | Kingston Frontenacs | 70 | 23 | 37 | 60 | 0.86 | 30 | 4 |
| 82. | Kaspars Daugavins (RW/C) | Brampton Steelheads | 61 | 18 | 42 | 60 | 0.98 | 64 | -19 |
| 83. | Bobby Sanguinetti (D) | Owen Sound Attack | 71 | 26 | 33 | 59 | 0.83 | 50 | -22 |
| 84. | Kevin Henderson (LW/C) | Kitchener Rangers | 65 | 37 | 21 | 58 | 0.89 | 82 | 7 |
| 85. | Steve Ward (D) | Plymouth Whalers | 86 | 16 | 42 | 58 | 0.67 | 100 | 27 |
| 86. | Brett Liscomb (LW) | Ottawa 67's | 67 | 26 | 31 | 57 | 0.85 | 111 | -3 |
| 87. | Peter Tsimikalis (C) | Kitchener Rangers | 40 | 19 | 38 | 57 | 1.43 | 20 | 19 |
| 88. | Bobby Bolt (LW) | Kingston Frontenacs | 67 | 22 | 34 | 56 | 0.84 | 74 | 2 |
| 89. | Andrew Hotham (D) | totals | 65 | 19 | 37 | 56 | 0.86 | 111 | -8 |
| Saginaw Spirit | Saginaw Spirit | 30 | 10 | 21 | 31 | 1.03 | 51 | 12 |
| Erie Otters | Erie Otters | 35 | 9 | 16 | 25 | 0.71 | 60 | -20 |
| 90. | Vladimir Nikiforov (LW/RW) | Barrie Colts | 68 | 22 | 33 | 55 | 0.81 | 32 | 2 |
| 91. | Kyle Raftis (D) | Peterborough Petes | 68 | 11 | 44 | 55 | 0.81 | 89 | -6 |
| 92. | Andrew Marshall (D) | Barrie Colts | 71 | 11 | 44 | 55 | 0.77 | 59 | 10 |
| 93. | Micheal Haley (C/W) | Brampton Steelheads | 68 | 30 | 24 | 54 | 0.79 | 174 | -18 |
| 94. | Ryan O'Marra (RW/C) | totals | 49 | 28 | 26 | 54 | 1.10 | 78 | -2 |
| Erie Otters | Erie Otters | 13 | 8 | 6 | 14 | 1.08 | 26 | -11 |
| Saginaw Spirit | Saginaw Spirit | 36 | 20 | 20 | 40 | 1.11 | 52 | 9 |
| 95. | Patrick Asselin (C/LW) | Saginaw Spirit | 74 | 27 | 27 | 54 | 0.73 | 30 | 11 |
| 96. | Brett Parnham (C) | Oshawa Generals | 74 | 27 | 27 | 54 | 0.73 | 71 | -10 |
| 97. | Jesse Messier (RW) | totals | 64 | 25 | 29 | 54 | 0.84 | 55 | 2 |
| Sudbury Wolves | Sudbury Wolves | 40 | 16 | 15 | 31 | 0.78 | 41 | 6 |
| Brampton Steelheads | Brampton Steelheads | 24 | 9 | 14 | 23 | 0.96 | 14 | -4 |
| 98. | Mickey Renaud (C) | Windsor Spitfires | 68 | 22 | 32 | 54 | 0.79 | 76 | -27 |
| 99. | Derek Joslin (D) | Ottawa 67's | 73 | 12 | 42 | 54 | 0.74 | 70 | -11 |
| 100. | Marc Staal (D) | Sudbury Wolves | 74 | 10 | 44 | 54 | 0.73 | 90 | 24 |