| 1. | Justin Azevedo (C/RW) | Kitchener Rangers | 67 | 43 | 81 | 124 | 1.85 | 69 | 24 |
| 2. | Brett MacLean (RW) | Oshawa Generals | 61 | 61 | 58 | 119 | 1.95 | 42 | 23 |
| 3. | John Tavares (C/LW) | Oshawa Generals | 59 | 40 | 78 | 118 | 2.00 | 69 | 22 |
| 4. | Luca Caputi (LW) | Niagara IceDogs | 66 | 51 | 60 | 111 | 1.68 | 107 | 26 |
| 5. | Steven Stamkos (C/W) | Sarnia Sting | 61 | 58 | 47 | 105 | 1.72 | 88 | 18 |
| 6. | Chris Terry (LW/RW) | Plymouth Whalers | 68 | 44 | 57 | 101 | 1.49 | 107 | 12 |
| 7. | Jack Combs (C/W) | Saginaw Spirit | 67 | 42 | 58 | 100 | 1.49 | 93 | 27 |
| 8. | Michael Swift (C/LW) | Niagara IceDogs | 68 | 38 | 62 | 100 | 1.47 | 130 | 36 |
| 9. | Dustin Jeffrey (C) | Soo Greyhounds | 56 | 38 | 59 | 97 | 1.73 | 30 | 25 |
| 10. | Josh Bailey (RW/C) | Windsor Spitfires | 67 | 29 | 67 | 96 | 1.43 | 32 | 30 |
| 11. | Justin DiBenedetto (C/LW) | Sarnia Sting | 58 | 39 | 54 | 93 | 1.60 | 61 | 12 |
| 12. | John Hughes (C/RW) | Brampton Battalion | 68 | 28 | 63 | 91 | 1.34 | 42 | 2 |
| 13. | Matt Beleskey (LW) | Belleville Bulls | 62 | 41 | 49 | 90 | 1.45 | 106 | 32 |
| 14. | Patrick Maroon (LW/RW) | London Knights | 64 | 35 | 55 | 90 | 1.41 | 57 | 13 |
| 15. | Ryan McDonough (C) | Saginaw Spirit | 66 | 45 | 44 | 89 | 1.35 | 85 | 29 |
| 16. | Brad Snetsinger (LW) | Windsor Spitfires | 68 | 37 | 52 | 89 | 1.31 | 45 | 18 |
| 17. | Cody Hodgson (C) | Brampton Battalion | 68 | 40 | 45 | 85 | 1.25 | 36 | 15 |
| 18. | Taylor Hall (LW/C) | Windsor Spitfires | 63 | 45 | 39 | 84 | 1.33 | 22 | 40 |
| 19. | Justin Hodgman (C) | Erie Otters | 64 | 37 | 43 | 80 | 1.25 | 75 | -10 |
| 20. | Adam Perry (LW) | Totals | 68 | 32 | 48 | 80 | 1.18 | 62 | 18 |
| London Knights | London Knights | 39 | 17 | 25 | 42 | 1.08 | 36 | -2 |
| Belleville Bulls | Belleville Bulls | 29 | 15 | 23 | 38 | 1.31 | 26 | 20 |
| 21. | Shawn Matthias (LW) | Belleville Bulls | 53 | 32 | 47 | 79 | 1.49 | 50 | 21 |
| 22. | Patrick Asselin (C/LW) | Totals | 63 | 41 | 37 | 78 | 1.24 | 34 | 0 |
| Saginaw Spirit | Saginaw Spirit | 15 | 9 | 6 | 15 | 1 | 11 | -4 |
| Oshawa Generals | Oshawa Generals | 48 | 32 | 31 | 63 | 1.31 | 23 | 4 |
| 23. | Bryan Cameron (C/RW) | Belleville Bulls | 68 | 41 | 37 | 78 | 1.15 | 56 | 23 |
| 24. | Nathan Moon (RW) | Kingston Frontenacs | 68 | 35 | 42 | 77 | 1.13 | 79 | -25 |
| 25. | Andrew Fournier (C) | Plymouth Whalers | 64 | 35 | 40 | 75 | 1.17 | 49 | 3 |
| 26. | Wayne Simmonds (RW) | Totals | 60 | 33 | 42 | 75 | 1.25 | 111 | 2 |
| Owen Sound Attack | Owen Sound Attack | 29 | 17 | 22 | 39 | 1.34 | 43 | -8 |
| Soo Greyhounds | Soo Greyhounds | 31 | 16 | 20 | 36 | 1.16 | 68 | 10 |
| 27. | Kaspars Daugavins (RW/C) | Brampton Steelheads | 62 | 40 | 34 | 74 | 1.19 | 42 | 11 |
| 28. | Mikkel Bødker (LW) | Kitchener Rangers | 62 | 29 | 44 | 73 | 1.18 | 14 | 6 |
| 29. | Nick Spaling (C/LW) | Kitchener Rangers | 56 | 38 | 34 | 72 | 1.29 | 18 | 7 |
| 30. | Ryan Wilson (D) | Sarnia Sting | 58 | 7 | 64 | 71 | 1.22 | 84 | 14 |
| 31. | Tomas Zaborsky (LW/C) | Saginaw Spirit | 68 | 31 | 39 | 70 | 1.03 | 42 | 16 |
| 32. | Bobby Sanguinetti (D) | Brampton Battalion | 61 | 29 | 41 | 70 | 1.15 | 38 | 10 |
| 33. | Greg Nemisz (RW) | Windsor Spitfires | 68 | 34 | 33 | 67 | 0.99 | 52 | 28 |
| 34. | Vladimir Nikiforov (LW/RW) | Totals | 51 | 25 | 42 | 67 | 1.31 | 21 | -10 |
| Barrie Colts | Barrie Colts | 36 | 21 | 32 | 53 | 1.47 | 17 | -4 |
| Sarnia Sting | Sarnia Sting | 15 | 4 | 10 | 14 | 0.93 | 4 | -6 |
| 35. | Zack Torquato (C) | Erie Otters | 66 | 25 | 42 | 67 | 1.02 | 112 | -33 |
| 36. | Brett Parnham (C) | Oshawa Generals | 68 | 32 | 34 | 66 | 0.97 | 35 | 3 |
| 37. | Matt Kang (LW) | Kingston Frontenacs | 66 | 30 | 36 | 66 | 1.00 | 41 | -19 |
| 38. | Chris MacKinnon (LW) | Totals | 64 | 25 | 40 | 65 | 1.02 | 87 | -17 |
| Soo Greyhounds | Soo Greyhounds | 29 | 11 | 18 | 29 | 1 | 34 | 1 |
| Owen Sound Attack | Owen Sound Attack | 35 | 14 | 22 | 36 | 1.03 | 53 | -18 |
| 39. | Nazem Kadri (C/LW) | Kitchener Rangers | 68 | 25 | 40 | 65 | 0.96 | 57 | 9 |
| 40. | Luke Lynes (C) | Brampton Battalion | 68 | 21 | 43 | 64 | 0.94 | 49 | 12 |
| 41. | Jan Mursak (C/RW) | Totals | 57 | 17 | 47 | 64 | 1.12 | 23 | 18 |
| Saginaw Spirit | Saginaw Spirit | 26 | 6 | 20 | 26 | 1 | 15 | 3 |
| Belleville Bulls | Belleville Bulls | 31 | 11 | 27 | 38 | 1.23 | 8 | 15 |
| 42. | Michael Del Zotto (D) | Oshawa Generals | 64 | 16 | 47 | 63 | 0.98 | 82 | 7 |
| 43. | Ryan Ellis (D)  | Windsor Spitfires | 63 | 15 | 48 | 63 | 1.00 | 51 | 30 |
| 44. | Jadran Beljo (LW) | London Knights | 53 | 33 | 29 | 62 | 1.17 | 40 | 16 |
| 45. | Jordan Foreman (D/C) | Niagara IceDogs | 65 | 28 | 34 | 62 | 0.95 | 155 | 29 |
| 46. | Akim Aliu (W/C/D) | London Knights | 60 | 28 | 33 | 61 | 1.02 | 133 | 10 |
| 47. | Cory Emmerton (C) | Totals | 54 | 25 | 36 | 61 | 1.13 | 16 | -9 |
| Kingston Frontenacs | Kingston Frontenacs | 24 | 13 | 18 | 31 | 1.29 | 6 | -14 |
| Brampton Battalion | Brampton Battalion | 30 | 12 | 18 | 30 | 1 | 10 | 5 |
| 48. | Phil Varone (C/W) | Totals | 67 | 15 | 46 | 61 | 0.91 | 26 | 14 |
| Kitchener Rangers | Kitchener Rangers | 36 | 5 | 20 | 25 | 0.69 | 12 | 8 |
| London Knights | London Knights | 31 | 10 | 26 | 36 | 1.16 | 14 | 6 |
| 49. | Zach Bogosian (D) | Peterborough Petes | 60 | 11 | 50 | 61 | 1.02 | 72 | 8 |
| 50. | Brandon Buck (LW) | Guelph Storm | 59 | 29 | 31 | 60 | 1.02 | 40 | 18 |
| 51. | Eric Tangradi (LW) | Belleville Bulls | 56 | 24 | 36 | 60 | 1.07 | 41 | 10 |
| 52. | Dale Mitchell (RW) | Oshawa Generals | 63 | 24 | 36 | 60 | 0.95 | 79 | -2 |
| 53. | Patrik Lusnak (LW/RW) | Sudbury Wolves | 58 | 20 | 39 | 59 | 1.02 | 56 | -11 |
| 54. | Matt Halischuk (RW) | Kitchener Rangers | 40 | 13 | 46 | 59 | 1.48 | 16 | 17 |
| 55. | Rafael Rotter (RW) | Guelph Storm | 68 | 13 | 46 | 59 | 0.87 | 109 | -1 |
| 56. | Jamie McGinn (LW) | Ottawa 67's | 51 | 29 | 29 | 58 | 1.14 | 54 | 10 |
| 57. | Logan Couture (C/LW)  | Ottawa 67's | 51 | 21 | 37 | 58 | 1.14 | 37 | 9 |
| 58. | Kevin Baker (C) | Totals | 69 | 27 | 30 | 57 | 0.83 | 18 | -12 |
| Sudbury Wolves | Sudbury Wolves | 40 | 21 | 18 | 39 | 0.98 | 16 | -16 |
| Oshawa Generals | Oshawa Generals | 29 | 6 | 12 | 18 | 0.62 | 2 | 4 |
| 59. | John Armstrong (C/RW) | Peterborough Petes | 65 | 21 | 36 | 57 | 0.88 | 77 | -10 |
| 60. | Matt Lyall (C) | Soo Greyhounds | 67 | 21 | 36 | 57 | 0.85 | 28 | 24 |
| 61. | Devin DiDiomete (LW) | Sarnia Sting | 56 | 23 | 33 | 56 | 1.00 | 216 | 5 |
| 62. | Robert Mignardi (RW) | Kingston Frontenacs | 66 | 19 | 37 | 56 | 0.85 | 58 | -14 |
| 63. | Justin Taylor (C) | London Knights | 68 | 26 | 29 | 55 | 0.81 | 79 | 4 |
| 64. | A.J. Jenks (C/W) | Plymouth Whalers | 68 | 26 | 29 | 55 | 0.81 | 94 | -13 |
| 65. | Yannick Weber (D) | Kitchener Rangers | 59 | 20 | 35 | 55 | 0.93 | 79 | 7 |
| 66. | Mike Duco (W/C) | Kitchener Rangers | 62 | 32 | 22 | 54 | 0.87 | 173 | 26 |
| 67. | Matt Carter (LW) | Owen Sound Attack | 61 | 30 | 24 | 54 | 0.89 | 52 | -22 |
| 68. | Alex Hutchings (RW/LW) | Barrie Colts | 68 | 29 | 25 | 54 | 0.79 | 48 | 7 |
| 69. | Matt Caria (C) | Totals | 46 | 22 | 31 | 53 | 1.15 | 66 | 10 |
| Brampton Steelheads | Brampton Steelheads | 20 | 8 | 14 | 22 | 1.1 | 35 | 2 |
| Soo Greyhounds | Soo Greyhounds | 26 | 14 | 17 | 31 | 1.19 | 31 | 8 |
| 70. | Alex Pietrangelo (D)  | Niagara IceDogs | 60 | 13 | 40 | 53 | 0.88 | 94 | 29 |
| 71. | Andrew Merrett (RW) | Niagara IceDogs | 65 | 21 | 31 | 52 | 0.80 | 33 | 17 |
| 72. | Brandon MacLean (C) | Soo Greyhounds | 68 | 21 | 31 | 52 | 0.76 | 42 | 24 |
| 73. | Ryan O'Reilly (C) | Erie Otters | 61 | 19 | 33 | 52 | 0.85 | 14 | -18 |
| 74. | Josh Brittain (D/C) | Kingston Frontenacs | 68 | 28 | 23 | 51 | 0.75 | 106 | -14 |
| 75. | Josh Godfrey (D) | Soo Greyhounds | 60 | 17 | 34 | 51 | 0.85 | 61 | 31 |
| 76. | Cory Tanaka (C) | Belleville Bulls | 68 | 13 | 38 | 51 | 0.75 | 26 | 33 |
| 77. | Matt Duchene (C/W) | Brampton Battalion | 64 | 30 | 20 | 50 | 0.78 | 22 | -2 |
| 78. | Andris Dzerins (C/W) | Kingston Frontenacs | 61 | 20 | 30 | 50 | 0.82 | 44 | -23 |
| 79. | Drew Doughty (D) | Guelph Storm | 58 | 13 | 37 | 50 | 0.86 | 68 | -1 |
| 80. | Justin Wallingford (D) | Kingston Frontenacs | 61 | 11 | 39 | 50 | 0.82 | 132 | -17 |
| 81. | Jared Staal (RW) | Sudbury Wolves | 60 | 21 | 28 | 49 | 0.82 | 44 | -11 |
| 82. | Graham McNabb (LW) | Brampton Battalion | 68 | 20 | 29 | 49 | 0.72 | 32 | 14 |
| 83. | Michael Pelech (C) | Brampton Steelheads | 68 | 17 | 32 | 49 | 0.72 | 72 | -10 |
| 84. | Wes Cunningham (D) | Plymouth Whalers | 55 | 6 | 43 | 49 | 0.89 | 100 | 5 |
| 85. | Pat Daley (RW) | Peterborough Petes | 62 | 28 | 20 | 48 | 0.77 | 24 | -2 |
| 86. | Anthony Nigro (C/W) | Guelph Storm | 67 | 24 | 24 | 48 | 0.72 | 65 | 1 |
| 87. | Scott Tregunna (RW) | Totals | 67 | 14 | 34 | 48 | 0.72 | 32 | -1 |
| Owen Sound Attack | Owen Sound Attack | 29 | 9 | 18 | 27 | 0.93 | 18 | -10 |
| Kitchener Rangers | Kitchener Rangers | 38 | 5 | 16 | 21 | 0.55 | 14 | 9 |
| 88. | Eric Regan (D) | Oshawa Generals | 67 | 8 | 40 | 48 | 0.72 | 56 | 11 |
| 89. | Ryan McGinnis (D) | Oshawa Generals | 64 | 6 | 42 | 48 | 0.75 | 115 | 12 |
| 90. | Jamie Arniel (C/RW) | Totals | 60 | 27 | 20 | 47 | 0.78 | 38 | -12 |
| Guelph Storm | Guelph Storm | 20 | 9 | 4 | 13 | 0.65 | 16 | -2 |
| Sarnia Sting | Sarnia Sting | 40 | 18 | 16 | 34 | 0.85 | 22 | -10 |
| 91. | Joey Hishon (C) | Owen Sound Attack | 63 | 20 | 27 | 47 | 0.75 | 38 | -34 |
| 92. | Harrison Reed (RW/C) | Totals | 69 | 14 | 33 | 47 | 0.68 | 40 | 5 |
| Sarnia Sting | Sarnia Sting | 28 | 6 | 12 | 18 | 0.64 | 20 | -1 |
| Guelph Storm | Guelph Storm | 41 | 8 | 21 | 29 | 0.71 | 20 | 6 |
| 93. | Nick Palmieri (RW) | Erie Otters | 50 | 28 | 18 | 46 | 0.92 | 122 | -30 |
| 94. | Philip McRae (C) | London Knights | 66 | 18 | 28 | 46 | 0.70 | 61 | -5 |
| 95. | Nigel Williams (D) | Totals | 67 | 15 | 31 | 46 | 0.69 | 100 | 18 |
| Saginaw Spirit | Saginaw Spirit | 29 | 5 | 19 | 24 | 0.83 | 60 | 2 |
| Belleville Bulls | Belleville Bulls | 38 | 10 | 12 | 22 | 0.58 | 40 | 16 |
| 96. | P.K. Subban (D) | Belleville Bulls | 58 | 8 | 38 | 46 | 0.79 | 100 | 19 |
| 97. | Tomas Marcinko (C) | Barrie Colts | 48 | 19 | 26 | 45 | 0.94 | 54 | -5 |
| 98. | Sean O'Connor (RW) | Totals | 56 | 17 | 28 | 45 | 0.80 | 52 | -7 |
| Plymouth Whalers | Plymouth Whalers | 8 | 0 | 2 | 2 | 0.25 | 6 | 1 |
| London Knights | London Knights | 48 | 17 | 26 | 43 | 0.9 | 46 | -8 |
| 99. | David Kolomatis (D) | Owen Sound Attack | 68 | 9 | 36 | 45 | 0.66 | 68 | -25 |
| 100. | James Livingston (RW/C) | Soo Greyhounds | 68 | 21 | 23 | 44 | 0.65 | 135 | 10 |