| 1. |  Jack Eichel (C) | | totals | 63 | 25 | 53 | 78 | 14 |
| | Vegas Golden Knights | NHL | 57 | 23 | 49 | 72 | 12 |
| | USA Olympics | OG | 6 | 2 | 4 | 6 | 2 |
| 2. | Matt Boldy (LW/RW) | | totals | 67 | 38 | 39 | 77 | 28 |
| | Minnesota Wild | NHL | 61 | 36 | 37 | 73 | 26 |
| | USA Olympics | OG | 6 | 2 | 2 | 4 | 2 |
| 3. | Tage Thompson (C/W) | | totals | 71 | 37 | 37 | 74 | 29 |
| | Buffalo Sabres | NHL | 65 | 34 | 36 | 70 | 29 |
| | USA Olympics | OG | 6 | 3 | 1 | 4 | 0 |
| 4. | Jason Robertson (LW/RW) | Dallas Stars | NHL | 64 | 34 | 40 | 74 | 22 |
| 5. | Zach Werenski (D) | | totals | 63 | 21 | 53 | 74 | 16 |
| | Columbus Blue Jackets | NHL | 57 | 20 | 48 | 68 | 12 |
| | USA Olympics | OG | 6 | 1 | 5 | 6 | 4 |
| 6. | Quinn Hughes (D) | | totals | 65 | 7 | 65 | 72 | 26 |
| |  Vancouver Canucks | NHL | 26 | 2 | 21 | 23 | 12 |
| | USA Olympics | OG | 6 | 1 | 7 | 8 | 0 |
| | Minnesota Wild | NHL | 33 | 4 | 37 | 41 | 14 |
| 7. | Kyle Connor (LW) | | totals | 65 | 28 | 43 | 71 | 16 |
| | Winnipeg Jets | NHL | 63 | 28 | 43 | 71 | 16 |
| | USA Olympics | OG | 2 | 0 | 0 | 0 | 0 |
| 8. | Lane Hutson (D) | Montréal Canadiens | NHL | 64 | 11 | 55 | 66 | 30 |
| 9. | Cole Caufield (LW/RW) | Montréal Canadiens | NHL | 63 | 37 | 27 | 64 | 14 |
| 10. | Alex DeBrincat (RW/LW) | Detroit Red Wings | NHL | 65 | 33 | 31 | 64 | 12 |
| 11. | Clayton Keller (RW/LW) | | totals | 69 | 19 | 45 | 64 | 22 |
| | Utah Mammoth | NHL | 65 | 19 | 45 | 64 | 22 |
| | USA Olympics | OG | 4 | 0 | 0 | 0 | 0 |
| 12. | Auston Matthews (C/LW) | | totals | 65 | 29 | 30 | 59 | 22 |
| | Toronto Maple Leafs | NHL | 59 | 26 | 26 | 52 | 18 |
| | USA Olympics | OG | 6 | 3 | 4 | 7 | 4 |
| 13. | Nick Schmaltz (C/RW) | Utah Mammoth | NHL | 65 | 24 | 35 | 59 | 26 |
| 14. | Dylan Larkin (C/LW) | | totals | 69 | 30 | 28 | 58 | 46 |
| | Detroit Red Wings | NHL | 63 | 28 | 27 | 55 | 42 |
| | USA Olympics | OG | 6 | 2 | 1 | 3 | 4 |
| 15. | Riley Barber (RW/LW) |  ERC Ingolstadt | DEL | 50 | 29 | 29 | 58 | 27 |
| 16. | Cutter Gauthier (LW/C) | Anaheim Ducks | NHL | 63 | 32 | 25 | 57 | 22 |
| 17. | Brock Nelson (C/LW) | | totals | 69 | 32 | 25 | 57 | 24 |
| | Colorado Avalanche | NHL | 63 | 30 | 24 | 54 | 24 |
| | USA Olympics | OG | 6 | 2 | 1 | 3 | 0 |
| 18. | Alex Tuch (RW/C) | Buffalo Sabres | NHL | 64 | 28 | 29 | 57 | 49 |
| 19. | Trevor Zegras (C/W) | Philadelphia Flyers | NHL | 64 | 22 | 31 | 53 | 42 |
| 20. | Jack Hughes (C/LW) | | totals | 49 | 19 | 33 | 52 | 6 |
| | New Jersey Devils | NHL | 43 | 15 | 30 | 45 | 4 |
| | USA Olympics | OG | 6 | 4 | 3 | 7 | 2 |
| 21. | Charlie Coyle (C/RW) | Columbus Blue Jackets | NHL | 64 | 16 | 35 | 51 | 10 |
| 22. | Jake Sanderson (D) | | totals | 68 | 11 | 39 | 50 | 8 |
| | Ottawa Senators | NHL | 62 | 11 | 37 | 48 | 8 |
| | USA Olympics | OG | 6 | 0 | 2 | 2 | 0 |
| 23. | Brady Tkachuk (LW) | | totals | 50 | 20 | 29 | 49 | 60 |
| | Ottawa Senators | NHL | 44 | 17 | 27 | 44 | 48 |
| | USA Olympics | OG | 6 | 3 | 2 | 5 | 12 |
| 24. | Patrick Brown (C/RW) | Providence Bruins | AHL | 56 | 17 | 32 | 49 | 46 |
| 25. | Zac Jones (D) | Rochester Americans | AHL | 45 | 8 | 41 | 49 | 10 |
| 26. | Vincent Trocheck (C) | | totals | 55 | 12 | 34 | 46 | 48 |
| | New York Rangers | NHL | 49 | 12 | 31 | 43 | 46 |
| | USA Olympics | OG | 6 | 0 | 3 | 3 | 2 |
| 27. | Charlie McAvoy (D) | | totals | 58 | 7 | 39 | 46 | 52 |
| | Boston Bruins | NHL | 52 | 7 | 39 | 46 | 46 |
| | USA Olympics | OG | 6 | 0 | 0 | 0 | 6 |
| 28. | Will Smith (C/RW) | San Jose Sharks | NHL | 49 | 19 | 26 | 45 | 14 |
| 29. | Jackson LaCombe (D) | | totals | 64 | 8 | 37 | 45 | 12 |
| | Anaheim Ducks | NHL | 64 | 8 | 37 | 45 | 12 |
| | USA Olympics | OG | 0 | 0 | 0 | 0 | 0 |
| 30. | Josh Doan (W/C) | Buffalo Sabres | NHL | 65 | 21 | 23 | 44 | 23 |
| 31. | Ryan Lasch (RW) |  Vålerenga | Norway | 39 | 14 | 30 | 44 | 12 |
| 32. | Alexander Chmelevski (C) | | totals | 62 | 18 | 24 | 42 | 18 |
| |  Salavat Yulaev Ufa | KHL | 6 | 1 | 2 | 3 | 2 |
| | Ak Bars Kazan | KHL | 56 | 17 | 22 | 39 | 16 |
| 33. | Isaac Howard (LW/RW) | | totals | 61 | 18 | 22 | 40 | 20 |
| | Edmonton Oilers | NHL | 28 | 2 | 3 | 5 | 12 |
| | Bakersfield Condors | AHL | 33 | 16 | 19 | 35 | 8 |
| 34. | Matty Beniers (C) | Seattle Kraken | NHL | 63 | 17 | 23 | 40 | 23 |
| 35. | Sean Farrell (C/LW) | Laval Rocket | AHL | 59 | 13 | 27 | 40 | 18 |
| 36. | Chris Kreider (LW/RW) | Anaheim Ducks | NHL | 58 | 21 | 18 | 39 | 22 |
| 37. | Vinni Lettieri (C/RW) | Toronto Marlies | AHL | 47 | 12 | 27 | 39 | 30 |
| 38. | Christian Dvorak (C/LW) | Philadelphia Flyers | NHL | 63 | 13 | 25 | 38 | 18 |
| 39. | T.J. Tynan (C/RW) | | totals | 53 | 3 | 35 | 38 | 38 |
| | Colorado Eagles | AHL | 52 | 3 | 35 | 38 | 38 |
| | Colorado Avalanche | NHL | 1 | 0 | 0 | 0 | 0 |
| 40. | Patrick Kane (RW/LW) | Detroit Red Wings | NHL | 50 | 10 | 27 | 37 | 14 |
| 41. | Andrew Copp (C/LW) | Detroit Red Wings | NHL | 65 | 8 | 29 | 37 | 22 |
| 42. | Scott Perunovich (D) | Tucson Roadrunners | AHL | 52 | 7 | 29 | 36 | 44 |
| 43. | Anders Lee (LW) | New York Islanders | NHL | 65 | 15 | 20 | 35 | 29 |
| 44. | Jimmy Vesey (LW/RW) |  Genève-Servette HC | NL | 52 | 14 | 21 | 35 | 16 |
| 45. | Shane Pinto (C) | Ottawa Senators | NHL | 54 | 17 | 17 | 34 | 38 |
| 46. | Ryan Leonard (C) | Washington Capitals | NHL | 59 | 13 | 21 | 34 | 34 |
| 47. | Justin Faulk (D) | | totals | 63 | 12 | 22 | 34 | 32 |
| | St. Louis Blues | NHL | 61 | 11 | 21 | 32 | 32 |
| | Detroit Red Wings | NHL | 2 | 1 | 1 | 2 | 0 |
| 48. | Rocco Grimaldi (LW/C) | SKA St. Petersburg | KHL | 62 | 13 | 20 | 33 | 26 |
| 49. | Jordan Oesterle (D) | Milwaukee Admirals | AHL | 55 | 6 | 27 | 33 | 24 |
| 50. | Kevin Labanc (RW/LW) |  Shanghai Dragons | KHL | 51 | 13 | 19 | 32 | 56 |
| 51. | Jacob Trouba (D) | Anaheim Ducks | NHL | 63 | 10 | 21 | 31 | 25 |
| 52. | Adam Fox (D) | New York Rangers | NHL | 37 | 4 | 27 | 31 | 14 |
| 53. | Kieffer Bellows (LW/RW) |  Brynäs IF | SHL | 50 | 15 | 15 | 30 | 31 |
| 54. | Matt Coronato (RW/LW) | Calgary Flames | NHL | 63 | 14 | 16 | 30 | 18 |
| 55. | Alexander Galchenyuk (C/RW) | Amur Khabarovsk | KHL | 48 | 13 | 17 | 30 | 12 |
| 56. | Conor Garland (RW/LW) | | totals | 53 | 11 | 19 | 30 | 30 |
| | Vancouver Canucks | NHL | 50 | 7 | 19 | 26 | 30 |
| | Columbus Blue Jackets | NHL | 3 | 4 | 0 | 4 | 0 |
| 57. | Frank Nazar (C/RW) | Chicago Blackhawks | NHL | 48 | 9 | 21 | 30 | 24 |
| 58. | Adam Clendening (D) | Shanghai Dragons | KHL | 62 | 3 | 27 | 30 | 64 |
| 59. | Joel Farabee (LW/RW) | Calgary Flames | NHL | 64 | 15 | 14 | 29 | 22 |
| 60. | Daniel Brickley (D) |  Tappara | Liiga | 48 | 5 | 24 | 29 | 14 |
| 61. | Luke Hughes (D) | New Jersey Devils | NHL | 54 | 5 | 24 | 29 | 28 |
| 62. | Logan Cooley (C/LW) | Utah Mammoth | NHL | 37 | 17 | 11 | 28 | 24 |
| 63. | Ryan Hartman (RW/C) | Minnesota Wild | NHL | 61 | 15 | 13 | 28 | 36 |
| 64. | Colin White (C/RW) | San Jose Barracuda | AHL | 32 | 11 | 17 | 28 | 24 |
| 65. | Andy Miele (C) | Fischtown Pinguins | DEL | 49 | 7 | 21 | 28 | 49 |
| 66. | James van Riemsdyk (LW/RW) | Detroit Red Wings | NHL | 56 | 15 | 12 | 27 | 12 |
| 67. | Ryan Donato (C/W) | Chicago Blackhawks | NHL | 64 | 14 | 13 | 27 | 36 |
| 68. | Ben Meyers (C/LW) | | totals | 49 | 15 | 11 | 26 | 11 |
| | Coachella Valley Firebirds | AHL | 11 | 9 | 4 | 13 | 2 |
| | Seattle Kraken | NHL | 38 | 6 | 7 | 13 | 9 |
| 69. | Blake Coleman (LW/RW) | Calgary Flames | NHL | 52 | 15 | 10 | 25 | 35 |
| 70. | Noah Hanifin (D) | | totals | 60 | 4 | 21 | 25 | 8 |
| | Vegas Golden Knights | NHL | 54 | 3 | 19 | 22 | 8 |
| | USA Olympics | OG | 6 | 1 | 2 | 3 | 0 |
| 71. | Ryan Shea (D) | Pittsburgh Penguins | NHL | 64 | 4 | 21 | 25 | 22 |
| 72. | Drew O'Connor (LW/RW) | Vancouver Canucks | NHL | 64 | 15 | 9 | 24 | 34 |
| 73. | Christian Wolanin (D) | Providence Bruins | AHL | 41 | 7 | 17 | 24 | 10 |
| 74. | Mason Lohrei (D) | Boston Bruins | NHL | 59 | 7 | 17 | 24 | 14 |
| 75. | Seth Jones (D) | Florida Panthers | NHL | 40 | 6 | 18 | 24 | 16 |
| 76. | Kevin Rooney (C/LW) | | totals | 37 | 13 | 9 | 22 | 6 |
| | Tucson Roadrunners | AHL | 36 | 12 | 9 | 21 | 6 |
| | Utah Mammoth | NHL | 1 | 1 | 0 | 1 | 0 |
| 77. | Sammy Walker (C/RW) | Tucson Roadrunners | AHL | 44 | 9 | 13 | 22 | 12 |
| 78. | Cam Fowler (D) | St. Louis Blues | NHL | 64 | 1 | 21 | 22 | 14 |
| 79. | Adam Gaudette (W/C) | San Jose Sharks | NHL | 49 | 14 | 7 | 21 | 16 |
| 80. | Karson Kuhlman (C/RW) | Rögle BK | SHL | 50 | 12 | 9 | 21 | 8 |
| 81. | Jack Drury (C/LW) | Colorado Avalanche | NHL | 63 | 8 | 13 | 21 | 20 |
| 82. | Nick Blankenburg (D) | | totals | 49 | 6 | 15 | 21 | 10 |
| | Nashville Predators | NHL | 49 | 6 | 15 | 21 | 10 |
| | Colorado Avalanche | NHL | - | - | - | - | - |
| 83. | Zeev Buium (D) | | totals | 58 | 5 | 16 | 21 | 18 |
| | Minnesota Wild | NHL | 31 | 3 | 11 | 14 | 8 |
| | Vancouver Canucks | NHL | 27 | 2 | 5 | 7 | 10 |
| 84. | Austin Watson (LW/RW) | Grand Rapids Griffins | AHL | 48 | 11 | 9 | 20 | 137 |
| 85. | J.T. Compher (W/C) | Detroit Red Wings | NHL | 65 | 8 | 12 | 20 | 23 |
| 86. | John Hayden (C/RW) | | totals | 53 | 11 | 8 | 19 | 115 |
| | Coachella Valley Firebirds | AHL | 50 | 11 | 8 | 19 | 113 |
| | Seattle Kraken | NHL | 3 | 0 | 0 | 0 | 2 |
| 87. | Henry Thrun (D) | | totals | 44 | 4 | 15 | 19 | 17 |
| | Toronto Marlies | AHL | 40 | 4 | 15 | 19 | 17 |
| | Toronto Maple Leafs | NHL | 4 | 0 | 0 | 0 | 0 |
| 88. | Will Butcher (D) | Cleveland Monsters | AHL | 48 | 3 | 16 | 19 | 8 |
| 89. | Jake McCabe (D) | Toronto Maple Leafs | NHL | 63 | 3 | 16 | 19 | 40 |
| 90. | Brady Skjei (D) | Nashville Predators | NHL | 64 | 1 | 18 | 19 | 26 |
| 91. | Michael Eyssimont (C/LW) | Boston Bruins | NHL | 50 | 8 | 10 | 18 | 31 |
| 92. | Trevor Moore (W/C) | Los Angeles Kings | NHL | 51 | 7 | 11 | 18 | 8 |
| 93. | Kyle Palmieri (RW) | New York Islanders | NHL | 25 | 6 | 12 | 18 | 8 |
| 94. | Nate Schmidt (D) | Utah Mammoth | NHL | 65 | 4 | 14 | 18 | 18 |
| 95. | Nick Jensen (D) | Ottawa Senators | NHL | 61 | 4 | 13 | 17 | 22 |
| 96. | Eric Robinson (LW/RW) | Carolina Hurricanes | NHL | 51 | 11 | 5 | 16 | 4 |
| 97. | Steve Moses (RW) | | totals | 39 | 6 | 10 | 16 | 10 |
| |  BK Mladá Boleslav | Czechia | 28 | 1 | 9 | 10 | 4 |
| | Mountfield HK | Czechia | 11 | 5 | 1 | 6 | 6 |
| 98. | Alex Vlasic (D) | Chicago Blackhawks | NHL | 63 | 2 | 14 | 16 | 13 |
| 99. | David Booth (LW/RW) |  Fife Flyers | EIHL | 11 | 11 | 4 | 15 | 4 |
| 100. | Drew LeBlanc (C) | Dresdner Eislöwen | DEL | 40 | 2 | 13 | 15 | 10 |
