| 1. | Connor McDavid (C) | Edmonton Oilers | 82 | 30 | 70 | 100 | 1.22 | 26 | 27 |
| 2. | Leon Draisaitl (C/W) | Edmonton Oilers | 82 | 29 | 48 | 77 | 0.94 | 20 | 7 |
| 3. | David Pastrnak (RW/LW) | Boston Bruins | 75 | 34 | 36 | 70 | 0.93 | 34 | 11 |
| 4. | Auston Matthews (C/LW) | Toronto Maple Leafs | 82 | 40 | 29 | 69 | 0.84 | 14 | 2 |
| 5. | Patrik Laine (LW/RW) | Winnipeg Jets | 73 | 36 | 28 | 64 | 0.88 | 26 | 7 |
| 6. | Nikolaj Ehlers (LW/RW) | Winnipeg Jets | 82 | 25 | 39 | 64 | 0.78 | 38 | 1 |
| 7. | William Nylander (W/C) | Toronto Maple Leafs | 81 | 22 | 39 | 61 | 0.75 | 32 | -3 |
| 8. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 77 | 19 | 42 | 61 | 0.79 | 38 | 0 |
| 9. | Jack Eichel (C) | Buffalo Sabres | 61 | 24 | 33 | 57 | 0.93 | 22 | -13 |
| 10. | Jonathan Drouin (LW/C) | Tampa Bay Lightning | 73 | 21 | 32 | 53 | 0.73 | 16 | -13 |
| 11. | Nathan MacKinnon (C/RW) | Colorado Avalanche | 82 | 16 | 37 | 53 | 0.65 | 16 | -14 |
| 12. | Aleksander Barkov (C/LW) | Florida Panthers | 61 | 21 | 31 | 52 | 0.85 | 10 | 13 |
| 13. | Bo Horvat (C) | Vancouver Canucks | 81 | 20 | 32 | 52 | 0.64 | 27 | -7 |
| 14. | Sebastian Aho (C/W) | Carolina Hurricanes | 82 | 24 | 25 | 49 | 0.60 | 26 | -1 |
| 15. | Matthew Tkachuk (LW/RW) | Calgary Flames | 76 | 13 | 35 | 48 | 0.63 | 105 | 14 |
| 16. | Sam Reinhart (C/RW) | Buffalo Sabres | 79 | 17 | 30 | 47 | 0.59 | 8 | -11 |
| 17. | Zach Werenski (D) | Columbus Blue Jackets | 78 | 11 | 36 | 47 | 0.60 | 14 | 17 |
| 18. | Brayden Point (C) | Tampa Bay Lightning | 68 | 18 | 22 | 40 | 0.59 | 14 | 4 |
| 19. | Mikko Rantanen (W/C) | Colorado Avalanche | 75 | 20 | 18 | 38 | 0.51 | 22 | -25 |
| 20. | Max Domi (C/W) | Arizona Coyotes | 59 | 9 | 29 | 38 | 0.64 | 40 | -9 |
| 21. | André Burakovsky (LW/RW) | Washington Capitals | 64 | 12 | 23 | 35 | 0.55 | 14 | 13 |
| 22. | Christian Dvorak (C/LW) | Arizona Coyotes | 78 | 15 | 18 | 33 | 0.42 | 22 | 7 |
| 23. | Dylan Larkin (C/LW) | Detroit Red Wings | 80 | 17 | 15 | 32 | 0.40 | 37 | -28 |
| 24. | Ivan Provorov (D) | Philadelphia Flyers | 82 | 6 | 24 | 30 | 0.37 | 34 | -7 |
| 25. | Robby Fabbri (C/W) | St. Louis Blues | 51 | 11 | 18 | 29 | 0.57 | 27 | -16 |
| 26. | Noah Hanifin (D) | Carolina Hurricanes | 81 | 4 | 25 | 29 | 0.36 | 26 | -19 |
| 27. | Artturi Lehkonen (LW/RW) | Montréal Canadiens | 73 | 18 | 10 | 28 | 0.38 | 8 | -1 |
| 28. | Nick Ritchie (LW) | Anaheim Ducks | 77 | 14 | 14 | 28 | 0.36 | 62 | 4 |
| 29. | Travis Konecny (RW/LW) | Philadelphia Flyers | 70 | 11 | 17 | 28 | 0.40 | 49 | -2 |
| 30. | Nick Schmaltz (C/RW) | Chicago Blackhawks | 61 | 6 | 22 | 28 | 0.46 | 6 | 10 |
| 31. | Sam Bennett (C/LW) | Calgary Flames | 81 | 13 | 13 | 26 | 0.32 | 75 | -16 |
| 32. | Anthony Beauvillier (LW/RW) | New York Islanders | 66 | 9 | 15 | 24 | 0.36 | 10 | 1 |
| 33. | Pavel Zacha (C/LW) | New Jersey Devils | 70 | 8 | 16 | 24 | 0.34 | 19 | -17 |
| 34. | Brendan Perlini (LW) | Arizona Coyotes | 57 | 14 | 7 | 21 | 0.37 | 20 | -4 |
| 35. | Aaron Ekblad (D) | Florida Panthers | 68 | 10 | 11 | 21 | 0.31 | 58 | -23 |
| 36. | Pavel Buchnevich (W/C) | New York Rangers | 41 | 8 | 12 | 20 | 0.49 | 13 | 6 |
| 37. | Kevin Labanc (RW/LW) | San Jose Sharks | 55 | 8 | 12 | 20 | 0.36 | 22 | 9 |
| 38. | Jakob Chychrun (D) | Arizona Coyotes | 68 | 7 | 13 | 20 | 0.29 | 47 | -14 |
| 39. | Josh Morrissey (D) | Winnipeg Jets | 82 | 6 | 14 | 20 | 0.24 | 38 | 6 |
| 40. | Miles Wood (LW/RW) | New Jersey Devils | 60 | 8 | 9 | 17 | 0.28 | 86 | -21 |
| 41. | Kevin Fiala (W/C) | Nashville Predators | 54 | 11 | 5 | 16 | 0.30 | 18 | 1 |
| 42. | Brandon Carlo (D) | Boston Bruins | 82 | 6 | 10 | 16 | 0.20 | 59 | 9 |
| 43. | Ondrej Kase (RW) | Anaheim Ducks | 53 | 5 | 10 | 15 | 0.28 | 18 | -1 |
| 44. | Anthony Duclair (W/C) | Arizona Coyotes | 58 | 5 | 10 | 15 | 0.26 | 14 | -7 |
| 45. | Tony DeAngelo (D) | Arizona Coyotes | 39 | 5 | 9 | 14 | 0.36 | 37 | -13 |
| 46. | Oliver Bjorkstrand (RW) | Columbus Blue Jackets | 26 | 6 | 7 | 13 | 0.50 | 6 | 4 |
| 47. | Nicolas Petan (C/LW) | Winnipeg Jets | 54 | 1 | 12 | 13 | 0.24 | 12 | -13 |
| 48. | Ivan Barbashyov (C/W) | St. Louis Blues | 30 | 5 | 7 | 12 | 0.40 | 2 | 5 |
| 49. | Lawson Crouse (LW/RW) | Arizona Coyotes | 72 | 5 | 7 | 12 | 0.17 | 48 | -20 |
| 50. | Darnell Nurse (D) | Edmonton Oilers | 44 | 5 | 6 | 11 | 0.25 | 33 | 0 |
| 51. | Denis Malgin (C/W) | Florida Panthers | 47 | 6 | 4 | 10 | 0.21 | 8 | -5 |
| 52. | Joshua Ho-Sang (RW) | New York Islanders | 21 | 4 | 6 | 10 | 0.48 | 12 | 1 |
| 53. | Nikita Zadorov (D) | Colorado Avalanche | 56 | 0 | 10 | 10 | 0.18 | 73 | -20 |
| 54. | Shea Theodore (D) | Anaheim Ducks | 34 | 2 | 7 | 9 | 0.26 | 28 | -6 |
| 55. | Jesse Puljujärvi (RW/LW) | Edmonton Oilers | 28 | 1 | 7 | 8 | 0.29 | 10 | 5 |
| 56. | Tyler Motte (C/W) | Chicago Blackhawks | 33 | 4 | 3 | 7 | 0.21 | 14 | 2 |
| 57. | Joel Eriksson Ek (C) | Minnesota Wild | 15 | 3 | 4 | 7 | 0.47 | 4 | 1 |
| 58. | Steven Santini (D) | New Jersey Devils | 38 | 2 | 5 | 7 | 0.18 | 14 | -6 |
| 59. | Remi Elie (C/LW) | Dallas Stars | 18 | 1 | 6 | 7 | 0.39 | 8 | 5 |
| 60. | Jared McCann (C/W) | Florida Panthers | 29 | 1 | 6 | 7 | 0.24 | 4 | -1 |
| 61. | Jakub Vrána (LW/RW) | Washington Capitals | 21 | 3 | 3 | 6 | 0.29 | 2 | 2 |
| 62. | Timo Meier (RW/LW) | San Jose Sharks | 34 | 3 | 3 | 6 | 0.18 | 10 | 1 |
| 63. | Adrian Kempe (W/C) | Los Angeles Kings | 25 | 2 | 4 | 6 | 0.24 | 6 | -3 |
| 64. | Brock Boeser (RW/LW) | Vancouver Canucks | 9 | 4 | 1 | 5 | 0.56 | 0 | 0 |
| 65. | J.T. Compher (W/C) | Colorado Avalanche | 21 | 3 | 2 | 5 | 0.24 | 4 | 0 |
| 66. | Kyle Connor (LW) | Winnipeg Jets | 20 | 2 | 3 | 5 | 0.25 | 4 | -7 |
| 67. | Gustav Forsling (D) | Chicago Blackhawks | 38 | 2 | 3 | 5 | 0.13 | 4 | 3 |
| 68. | Julius Honka (D) | Dallas Stars | 16 | 1 | 4 | 5 | 0.31 | 4 | -4 |
| 69. | Michael McCarron (RW/C) | Montréal Canadiens | 31 | 1 | 4 | 5 | 0.16 | 41 | -4 |
| 70. | Nicholas Baptiste (C/RW) | Buffalo Sabres | 14 | 3 | 1 | 4 | 0.29 | 6 | 1 |
| 71. | Justin Bailey (RW/LW) | Buffalo Sabres | 32 | 2 | 2 | 4 | 0.13 | 4 | 0 |
| 72. | John Quenneville (LW) | New Jersey Devils | 12 | 1 | 3 | 4 | 0.33 | 2 | 1 |
| 73. | John Hayden (C/RW) | Chicago Blackhawks | 12 | 1 | 3 | 4 | 0.33 | 4 | 3 |
| 74. | Curtis Lazar (C/W) | totals | 37 | 1 | 3 | 4 | 0.11 | 4 | -8 |
| Ottawa Senators | Ottawa Senators | 33 | 0 | 1 | 1 | 0.03 | 4 | -10 |
| Calgary Flames | Calgary Flames | 4 | 1 | 2 | 3 | 0.75 | 0 | 2 |
| 75. | Christian Fischer (RW/C) | Arizona Coyotes | 7 | 3 | 0 | 3 | 0.43 | 0 | 0 |
| 76. | Nikolai Goldobin (RW/LW) | totals | 14 | 3 | 0 | 3 | 0.21 | 0 | 0 |
| San Jose Sharks | San Jose Sharks | 2 | 0 | 0 | 0 | 0.00 | 0 | -1 |
| Vancouver Canucks | Vancouver Canucks | 12 | 3 | 0 | 3 | 0.25 | 0 | 1 |
| 77. | Adam Erne (LW/RW) | Tampa Bay Lightning | 26 | 3 | 0 | 3 | 0.12 | 11 | -9 |
| 78. | Frédérik Gauthier (C) | Toronto Maple Leafs | 21 | 2 | 1 | 3 | 0.14 | 23 | 2 |
| 79. | Laurent Dauphin (C/LW) | Arizona Coyotes | 24 | 2 | 1 | 3 | 0.13 | 12 | -2 |
| 80. | Jason Dickinson (C/LW) | Dallas Stars | 10 | 2 | 0 | 2 | 0.20 | 0 | -3 |
| 81. | Mirco Müller (D) | San Jose Sharks | 4 | 1 | 1 | 2 | 0.50 | 0 | 2 |
| 82. | Anton Blidh (LW/RW) | Boston Bruins | 19 | 1 | 1 | 2 | 0.11 | 7 | -2 |
| 83. | Clayton Keller (RW/LW) | Arizona Coyotes | 3 | 0 | 2 | 2 | 0.67 | 0 | -3 |
| 84. | Lucas Wallmark (C) | Carolina Hurricanes | 8 | 0 | 2 | 2 | 0.25 | 2 | 1 |
| 85. | Peter Cehlárik (LW) | Boston Bruins | 11 | 0 | 2 | 2 | 0.18 | 0 | 0 |
| 86. | Valentin Zykov (LW/RW) | Carolina Hurricanes | 2 | 1 | 0 | 1 | 0.50 | 0 | 1 |
| 87. | Nikita Scherbak (LW/RW) | Montréal Canadiens | 3 | 1 | 0 | 1 | 0.33 | 0 | 1 |
| 88. | Tyson Jost (C/LW) | Colorado Avalanche | 6 | 1 | 0 | 1 | 0.17 | 0 | -5 |
| 89. | Kasperi Kapanen (W/C) | Toronto Maple Leafs | 8 | 1 | 0 | 1 | 0.13 | 0 | -2 |
| 90. | Gabriel Carlsson (D) | Columbus Blue Jackets | 2 | 0 | 1 | 1 | 0.50 | 0 | -2 |
| 91. | Sergei Tolchinsky (RW/LW) | Carolina Hurricanes | 2 | 0 | 1 | 1 | 0.50 | 0 | 0 |
| 92. | Ian McCoshen (D) | Florida Panthers | 3 | 0 | 1 | 1 | 0.33 | 0 | 0 |
| 93. | Alexander Nylander (W/C) | Buffalo Sabres | 4 | 0 | 1 | 1 | 0.25 | 0 | -2 |
| 94. | A.J. Greer (LW/RW) | Colorado Avalanche | 5 | 0 | 1 | 1 | 0.20 | 4 | -2 |
| 95. | Dylan Strome (C) | Arizona Coyotes | 7 | 0 | 1 | 1 | 0.14 | 0 | -5 |
| 96. | Hudson Fasching (RW/LW) | Buffalo Sabres | 10 | 0 | 1 | 1 | 0.10 | 2 | -1 |
| 97. | Jake Virtanen (RW/LW) | Vancouver Canucks | 10 | 0 | 1 | 1 | 0.10 | 2 | 1 |
| 98. | Charlie McAvoy (D) | Boston Bruins | 0 | 0 | 0 | 0 | - | 0 | 0 |
| 99. | Thomas Chabot (D) | Ottawa Senators | 1 | 0 | 0 | 0 | 0.00 | 0 | -2 |
| 100. | Rasmus Andersson (D) | Calgary Flames | 1 | 0 | 0 | 0 | 0.00 | 0 | -1 |