| 1. | Connor McDavid (C) | Edmonton Oilers | 82 | 41 | 67 | 108 | 1.32 | 26 | 20 |
| 2. | Mathew Barzal (C/RW) | New York Islanders | 82 | 22 | 63 | 85 | 1.04 | 30 | 1 |
| 3. | Mikko Rantanen (W/C) | Colorado Avalanche | 81 | 29 | 55 | 84 | 1.04 | 34 | 0 |
| 4. | David Pastrnak (RW/LW) | Boston Bruins | 82 | 35 | 45 | 80 | 0.98 | 37 | 10 |
| 5. | Patrik Laine (LW/RW) | Winnipeg Jets | 82 | 44 | 26 | 70 | 0.85 | 24 | 8 |
| 6. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 82 | 22 | 47 | 69 | 0.84 | 26 | -1 |
| 7. | Brayden Point (C) | Tampa Bay Lightning | 82 | 32 | 34 | 66 | 0.80 | 24 | 18 |
| 8. | Sebastian Aho (C/W) | Carolina Hurricanes | 78 | 29 | 36 | 65 | 0.83 | 24 | 4 |
| 9. | Clayton Keller (RW/LW) | Arizona Coyotes | 82 | 23 | 42 | 65 | 0.79 | 24 | -7 |
| 10. | Jack Eichel (C) | Buffalo Sabres | 67 | 25 | 39 | 64 | 0.96 | 32 | -25 |
| 11. | Auston Matthews (C/LW) | Toronto Maple Leafs | 62 | 34 | 29 | 63 | 1.02 | 12 | 25 |
| 12. | Dylan Larkin (C/LW) | Detroit Red Wings | 82 | 16 | 47 | 63 | 0.77 | 61 | -9 |
| 13. | William Nylander (W/C) | Toronto Maple Leafs | 82 | 20 | 41 | 61 | 0.74 | 10 | 20 |
| 14. | Nikolaj Ehlers (LW/RW) | Winnipeg Jets | 82 | 29 | 31 | 60 | 0.73 | 26 | 14 |
| 15. | Kyle Connor (LW) | Winnipeg Jets | 76 | 31 | 26 | 57 | 0.75 | 16 | 8 |
| 16. | Brock Boeser (RW/LW) | Vancouver Canucks | 62 | 29 | 26 | 55 | 0.89 | 16 | -5 |
| 17. | Alex DeBrincat (RW/LW) | Chicago Blackhawks | 82 | 28 | 24 | 52 | 0.63 | 6 | 6 |
| 18. | Nick Schmaltz (C/RW) | Chicago Blackhawks | 78 | 21 | 31 | 52 | 0.67 | 18 | 1 |
| 19. | Nico Hischier (C/LW) | New Jersey Devils | 82 | 20 | 32 | 52 | 0.63 | 26 | 10 |
| 20. | Matthew Tkachuk (LW/RW) | Calgary Flames | 68 | 24 | 25 | 49 | 0.72 | 61 | -1 |
| 21. | Kevin Fiala (W/C) | Nashville Predators | 80 | 23 | 25 | 48 | 0.60 | 26 | 20 |
| 22. | Pierre-Luc Dubois (C) | Columbus Blue Jackets | 82 | 20 | 28 | 48 | 0.59 | 49 | 8 |
| 23. | Travis Konecny (RW/LW) | Philadelphia Flyers | 81 | 24 | 23 | 47 | 0.58 | 46 | 17 |
| 24. | Jake DeBrusk (LW) | Boston Bruins | 70 | 16 | 27 | 43 | 0.61 | 19 | 13 |
| 25. | Ivan Provorov (D) | Philadelphia Flyers | 82 | 17 | 24 | 41 | 0.50 | 20 | 17 |
| 26. | Mikhail Sergachyov (D) | Tampa Bay Lightning | 79 | 9 | 31 | 40 | 0.51 | 38 | 11 |
| 27. | Aaron Ekblad (D) | Florida Panthers | 82 | 16 | 22 | 38 | 0.46 | 71 | 9 |
| 28. | Zach Werenski (D) | Columbus Blue Jackets | 77 | 16 | 21 | 37 | 0.48 | 16 | 8 |
| 29. | Adrian Kempe (W/C) | Los Angeles Kings | 81 | 16 | 21 | 37 | 0.46 | 49 | 11 |
| 30. | Christian Dvorak (C/LW) | Arizona Coyotes | 78 | 15 | 22 | 37 | 0.47 | 22 | -19 |
| 31. | Alex Tuch (RW) | Vegas Golden Knights | 78 | 15 | 22 | 37 | 0.47 | 27 | 3 |
| 32. | Anthony Beauvillier (LW/RW) | New York Islanders | 71 | 21 | 15 | 36 | 0.51 | 16 | 2 |
| 33. | Timo Meier (RW/LW) | San Jose Sharks | 81 | 21 | 15 | 36 | 0.44 | 51 | 2 |
| 34. | Jesper Bratt (LW/RW) | New Jersey Devils | 74 | 13 | 22 | 35 | 0.47 | 18 | -16 |
| 35. | Christian Fischer (RW/C) | Arizona Coyotes | 79 | 15 | 18 | 33 | 0.42 | 14 | -17 |
| 36. | Noah Hanifin (D) | Carolina Hurricanes | 79 | 10 | 22 | 32 | 0.41 | 21 | -20 |
| 37. | Charlie McAvoy (D) | Boston Bruins | 63 | 7 | 25 | 32 | 0.51 | 53 | 20 |
| 38. | Brendan Perlini (LW) | Arizona Coyotes | 74 | 17 | 13 | 30 | 0.41 | 28 | -2 |
| 39. | Nolan Patrick (C) | Philadelphia Flyers | 73 | 13 | 17 | 30 | 0.41 | 30 | 1 |
| 40. | Jared McCann (C/W) | Florida Panthers | 68 | 9 | 19 | 28 | 0.41 | 30 | 11 |
| 41. | Jakub Vrána (LW/RW) | Washington Capitals | 73 | 13 | 14 | 27 | 0.37 | 12 | 2 |
| 42. | Sam Bennett (C/LW) | Calgary Flames | 82 | 11 | 15 | 26 | 0.32 | 59 | -18 |
| 43. | Thomas Chabot (D) | Ottawa Senators | 63 | 9 | 16 | 25 | 0.40 | 14 | -12 |
| 44. | Pavel Zacha (C/LW) | New Jersey Devils | 69 | 8 | 17 | 25 | 0.36 | 30 | -3 |
| 45. | Vince Dunn (D) | St. Louis Blues | 75 | 5 | 19 | 24 | 0.32 | 20 | 1 |
| 46. | Samuel Girard (D) | totals | 73 | 4 | 19 | 23 | 0.32 | 8 | -11 |
| Nashville Predators | Nashville Predators | 5 | 1 | 2 | 3 | 0.60 | 2 | -3 |
| Colorado Avalanche | Colorado Avalanche | 68 | 3 | 17 | 20 | 0.29 | 6 | -8 |
| 47. | Sonny Milano (LW) | Columbus Blue Jackets | 55 | 14 | 8 | 22 | 0.40 | 10 | -8 |
| 48. | Tyson Jost (C/LW) | Colorado Avalanche | 65 | 12 | 10 | 22 | 0.34 | 26 | -10 |
| 49. | Denis Malgin (C/W) | Florida Panthers | 51 | 11 | 11 | 22 | 0.43 | 6 | 4 |
| 50. | Jesse Puljujärvi (RW/LW) | Edmonton Oilers | 65 | 12 | 8 | 20 | 0.31 | 14 | -1 |
| 51. | Jake Virtanen (RW/LW) | Vancouver Canucks | 75 | 10 | 10 | 20 | 0.27 | 46 | -11 |
| 52. | Joel Eriksson Ek (C) | Minnesota Wild | 75 | 6 | 10 | 16 | 0.21 | 22 | 2 |
| 53. | Jack Roslovic (C/RW) | Winnipeg Jets | 31 | 5 | 9 | 14 | 0.45 | 2 | 5 |
| 54. | Jakob Chychrun (D) | Arizona Coyotes | 50 | 4 | 10 | 14 | 0.28 | 16 | 2 |
| 55. | Gustav Forsling (D) | Chicago Blackhawks | 41 | 3 | 10 | 13 | 0.32 | 8 | -2 |
| 56. | Travis Dermott (D) | Toronto Maple Leafs | 37 | 1 | 12 | 13 | 0.35 | 8 | 16 |
| 57. | Anders Bjork (C/LW) | Boston Bruins | 30 | 4 | 8 | 12 | 0.40 | 6 | 2 |
| 58. | Joshua Ho-Sang (RW) | New York Islanders | 22 | 2 | 10 | 12 | 0.55 | 2 | -7 |
| 59. | Anthony Cirelli (C) | Tampa Bay Lightning | 18 | 5 | 6 | 11 | 0.61 | 6 | 11 |
| 60. | Travis Sanheim (D) | Philadelphia Flyers | 49 | 2 | 8 | 10 | 0.20 | 20 | -6 |
| 61. | Kasperi Kapanen (W/C) | Toronto Maple Leafs | 38 | 7 | 2 | 9 | 0.24 | 4 | -1 |
| 62. | Ryan Donato (C/W) | Boston Bruins | 12 | 5 | 4 | 9 | 0.75 | 2 | 2 |
| 63. | Dylan Strome (C) | Arizona Coyotes | 21 | 4 | 5 | 9 | 0.43 | 8 | 4 |
| 64. | Tage Thompson (C/W) | St. Louis Blues | 41 | 3 | 6 | 9 | 0.22 | 12 | -12 |
| 65. | Michael Amadio (W/C) | Los Angeles Kings | 37 | 4 | 4 | 8 | 0.22 | 8 | -2 |
| 66. | Haydn Fleury (D) | Carolina Hurricanes | 67 | 0 | 8 | 8 | 0.12 | 14 | -2 |
| 67. | Victor Mete (D) | Montréal Canadiens | 49 | 0 | 7 | 7 | 0.14 | 4 | 5 |
| 68. | Colin White (C/RW) | Ottawa Senators | 21 | 2 | 4 | 6 | 0.29 | 8 | 1 |
| 69. | Oskar Lindblom (LW) | Philadelphia Flyers | 23 | 2 | 4 | 6 | 0.26 | 8 | 4 |
| 70. | Brandon Carlo (D) | Boston Bruins | 76 | 0 | 6 | 6 | 0.08 | 45 | 10 |
| 71. | Casey Mittelstadt (C/LW) | Buffalo Sabres | 6 | 1 | 4 | 5 | 0.83 | 2 | 1 |
| 72. | Brendan Guhle (D) | Buffalo Sabres | 18 | 0 | 5 | 5 | 0.28 | 10 | -6 |
| 73. | Yevgeni Svechnikov (RW/LW) | Detroit Red Wings | 14 | 2 | 2 | 4 | 0.29 | 8 | -2 |
| 74. | Luke Kunin (C/W) | Minnesota Wild | 19 | 2 | 2 | 4 | 0.21 | 13 | -3 |
| 75. | Ethan Bear (D) | Edmonton Oilers | 18 | 1 | 3 | 4 | 0.22 | 10 | -11 |
| 76. | Filip Chlapík (C/LW) | Ottawa Senators | 20 | 1 | 3 | 4 | 0.20 | 4 | -5 |
| 77. | Sebastian Aho (D) | New York Islanders | 22 | 1 | 3 | 4 | 0.18 | 6 | -5 |
| 78. | Marcus Pettersson (D) | Anaheim Ducks | 22 | 1 | 3 | 4 | 0.18 | 6 | 5 |
| 79. | Warren Foegele (LW/C) | Carolina Hurricanes | 2 | 2 | 1 | 3 | 1.50 | 0 | 3 |
| 80. | Daniel Sprong (LW/RW) | Pittsburgh Penguins | 8 | 2 | 1 | 3 | 0.38 | 0 | 2 |
| 81. | Filip Chytil (C) | New York Rangers | 9 | 1 | 2 | 3 | 0.33 | 4 | -5 |
| 82. | Samuel Blais (LW/RW) | St. Louis Blues | 11 | 1 | 2 | 3 | 0.27 | 6 | 1 |
| 83. | Noah Juulsen (D) | Montréal Canadiens | 23 | 1 | 2 | 3 | 0.13 | 4 | 1 |
| 84. | Joe Hicketts (D) | Detroit Red Wings | 5 | 0 | 3 | 3 | 0.60 | 2 | 5 |
| 85. | Kailer Yamamoto (RW/LW) | Edmonton Oilers | 9 | 0 | 3 | 3 | 0.33 | 2 | -2 |
| 86. | Roland McKeown (D) | Carolina Hurricanes | 10 | 0 | 3 | 3 | 0.30 | 19 | 3 |
| 87. | A.J. Greer (LW/RW) | Colorado Avalanche | 17 | 0 | 3 | 3 | 0.18 | 29 | 2 |
| 88. | Matthew Highmore (C/W) | Chicago Blackhawks | 13 | 2 | 0 | 2 | 0.15 | 0 | -4 |
| 89. | Lias Andersson (C/LW) | New York Rangers | 7 | 1 | 1 | 2 | 0.29 | 0 | 1 |
| 90. | Louie Belpedio (D) | Minnesota Wild | 1 | 0 | 2 | 2 | 2.00 | 0 | 1 |
| 91. | Gabriel Carlsson (D) | Columbus Blue Jackets | 14 | 0 | 2 | 2 | 0.14 | 4 | 0 |
| 92. | Sami Niku (D) | Winnipeg Jets | 1 | 1 | 0 | 1 | 1.00 | 0 | 0 |
| 93. | Alexander Nylander (W/C) | Buffalo Sabres | 3 | 1 | 0 | 1 | 0.33 | 0 | -3 |
| 94. | Henrik Borgström (C/W) | Florida Panthers | 4 | 1 | 0 | 1 | 0.25 | 0 | -1 |
| 95. | Blake Hillman (D) | Chicago Blackhawks | 4 | 1 | 0 | 1 | 0.25 | 0 | -1 |
| 96. | Owen Tippett (RW/LW) | Florida Panthers | 7 | 1 | 0 | 1 | 0.14 | 0 | -6 |
| 97. | Brendan Lemieux (LW) | Winnipeg Jets | 9 | 1 | 0 | 1 | 0.11 | 21 | 2 |
| 98. | Lawson Crouse (LW/RW) | Arizona Coyotes | 11 | 1 | 0 | 1 | 0.09 | 7 | -6 |
| 99. | Shane Gersich (C/LW) | Washington Capitals | 3 | 0 | 1 | 1 | 0.33 | 0 | -1 |
| 100. | Logan Brown (C/LW) | Ottawa Senators | 4 | 0 | 1 | 1 | 0.25 | 0 | 0 |