| 1. | Connor McDavid (C) | Edmonton Oilers | 101 | 40 | 134 | 174 | 1.72 | 40 | 47 |
| 2. | Nathan MacKinnon (C/RW) | Colorado Avalanche | 93 | 55 | 99 | 154 | 1.66 | 46 | 34 |
| 3. | Evan Bouchard (D) | Edmonton Oilers | 106 | 24 | 90 | 114 | 1.08 | 54 | 48 |
| 4. | Sam Reinhart (C/RW) | Florida Panthers | 106 | 67 | 43 | 110 | 1.04 | 43 | 27 |
| 5. | Cale Makar (D) | Colorado Avalanche | 88 | 26 | 79 | 105 | 1.19 | 16 | 12 |
| 6. | Zach Hyman (W/C) | Edmonton Oilers | 105 | 70 | 29 | 99 | 0.94 | 60 | 48 |
| 7. | Brayden Point (C) | Tampa Bay Lightning | 86 | 48 | 47 | 95 | 1.10 | 16 | -17 |
| 8. | Sidney Crosby (C) | Pittsburgh Penguins | 82 | 42 | 52 | 94 | 1.15 | 40 | 7 |
| 9. | Carter Verhaeghe (C/LW) | Florida Panthers | 100 | 45 | 48 | 93 | 0.93 | 56 | 12 |
| 10. | Ryan Nugent-Hopkins (C/W) | Edmonton Oilers | 105 | 25 | 64 | 89 | 0.85 | 44 | 8 |
| 11. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 76 | 27 | 61 | 88 | 1.16 | 20 | 22 |
| 12. | Steven Stamkos (C/W) | Tampa Bay Lightning | 84 | 45 | 42 | 87 | 1.04 | 36 | -26 |
| 13. | Robert Thomas (C/RW) | St. Louis Blues | 82 | 26 | 60 | 86 | 1.05 | 48 | 9 |
| 14. | Mathew Barzal (C/RW) | New York Islanders | 85 | 25 | 60 | 85 | 1.00 | 38 | -5 |
| 15. | Wyatt Johnston (C/RW) | Dallas Stars | 101 | 42 | 39 | 81 | 0.80 | 40 | 18 |
| 16. | Brandon Hagel (LW) | Tampa Bay Lightning | 87 | 29 | 51 | 80 | 0.92 | 81 | -4 |
| 17. | Mark Scheifele (C) | Winnipeg Jets | 79 | 27 | 51 | 78 | 0.99 | 57 | 13 |
| 18. | Nick Suzuki (C) | Montréal Canadiens | 82 | 33 | 44 | 77 | 0.94 | 36 | -14 |
| 19. | Brad Marchand (LW) | Boston Bruins | 93 | 32 | 45 | 77 | 0.83 | 94 | 5 |
| 20. | Seth Jarvis (C/W) | Carolina Hurricanes | 92 | 38 | 38 | 76 | 0.83 | 14 | 25 |
| 21. | Nazem Kadri (C/LW) | Calgary Flames | 82 | 29 | 46 | 75 | 0.91 | 43 | 0 |
| 22. | Jamie Benn (LW/C) | Dallas Stars | 101 | 25 | 50 | 75 | 0.74 | 47 | 13 |
| 23. | Jonathan Marchessault (LW/RW) | Vegas Golden Knights | 89 | 44 | 29 | 73 | 0.82 | 42 | -1 |
| 24. | Josh Morrissey (D) | Winnipeg Jets | 86 | 13 | 60 | 73 | 0.85 | 46 | 31 |
| 25. | Alexis Lafrenière (RW/LW) | New York Rangers | 98 | 36 | 35 | 71 | 0.72 | 46 | 4 |
| 26. | Bo Horvat (C) | New York Islanders | 86 | 34 | 37 | 71 | 0.83 | 39 | -3 |
| 27. | Ryan O'Reilly (C) | Nashville Predators | 88 | 27 | 44 | 71 | 0.81 | 18 | 5 |
| 28. | Matt Duchene (C/W) | Dallas Stars | 99 | 27 | 44 | 71 | 0.72 | 26 | 15 |
| 29. | Noah Dobson (D) | New York Islanders | 84 | 10 | 61 | 71 | 0.85 | 42 | 11 |
| 30. | Dylan Strome (C) | Washington Capitals | 86 | 28 | 41 | 69 | 0.80 | 22 | -14 |
| 31. | Travis Konecny (RW/LW) | Philadelphia Flyers | 76 | 33 | 35 | 68 | 0.89 | 67 | 4 |
| 32. | Jordan Kyrou (C/RW) | St. Louis Blues | 82 | 31 | 36 | 67 | 0.82 | 22 | -12 |
| 33. | John Tavares (C/LW) | Toronto Maple Leafs | 87 | 30 | 37 | 67 | 0.77 | 32 | 2 |
| 34. | Drake Batherson (RW/C) | Ottawa Senators | 82 | 28 | 38 | 66 | 0.80 | 42 | -9 |
| 35. | Tyler Seguin (C/RW) | Dallas Stars | 87 | 30 | 35 | 65 | 0.75 | 28 | 19 |
| 36. | Claude Giroux (W/C) | Ottawa Senators | 82 | 21 | 43 | 64 | 0.78 | 26 | -14 |
| 37. | Jared McCann (C/W) | Seattle Kraken | 80 | 29 | 33 | 62 | 0.78 | 31 | -10 |
| 38. | Mike Matheson (D) | Montréal Canadiens | 82 | 11 | 51 | 62 | 0.76 | 58 | -24 |
| 39. | Connor Bedard (C/LW) | Chicago Blackhawks | 68 | 22 | 39 | 61 | 0.90 | 28 | -44 |
| 40. | Morgan Rielly (D) | Toronto Maple Leafs | 79 | 7 | 54 | 61 | 0.77 | 27 | 9 |
| 41. | Sean Monahan (C/LW) | totals | 88 | 26 | 34 | 60 | 0.68 | 12 | -2 |
| Montréal Canadiens | Montréal Canadiens | 49 | 13 | 22 | 35 | 0.71 | 10 | -10 |
| Winnipeg Jets | Winnipeg Jets | 39 | 13 | 12 | 25 | 0.64 | 2 | 8 |
| 42. | Quinton Byfield (C/LW) | Los Angeles Kings | 85 | 20 | 39 | 59 | 0.69 | 46 | 23 |
| 43. | Jonathan Drouin (LW/C) | Colorado Avalanche | 82 | 19 | 40 | 59 | 0.72 | 30 | 11 |
| 44. | Adam Henrique (C/LW) | totals | 99 | 28 | 30 | 58 | 0.59 | 39 | 12 |
| Anaheim Ducks | Anaheim Ducks | 60 | 18 | 24 | 42 | 0.70 | 33 | 3 |
| Edmonton Oilers | Edmonton Oilers | 39 | 10 | 6 | 16 | 0.41 | 6 | 9 |
| 45. | Mason Marchment (LW/C) | Dallas Stars | 94 | 25 | 33 | 58 | 0.62 | 64 | 19 |
| 46. | Tyler Toffoli (RW/C) | totals | 84 | 35 | 22 | 57 | 0.68 | 14 | -8 |
| New Jersey Devils | New Jersey Devils | 61 | 26 | 18 | 44 | 0.72 | 12 | -15 |
| Winnipeg Jets | Winnipeg Jets | 23 | 9 | 4 | 13 | 0.57 | 2 | 7 |
| 47. | Mark Stone (RW) | Vegas Golden Knights | 63 | 19 | 37 | 56 | 0.89 | 24 | -1 |
| 48. | Devon Toews (D) | Colorado Avalanche | 92 | 13 | 43 | 56 | 0.61 | 20 | 32 |
| 49. | Sam Bennett (C/LW) | Florida Panthers | 88 | 27 | 28 | 55 | 0.63 | 112 | 16 |
| 50. | Michael Bunting (LW/RW) | totals | 81 | 19 | 36 | 55 | 0.68 | 57 | -19 |
| Carolina Hurricanes | Carolina Hurricanes | 60 | 13 | 23 | 36 | 0.60 | 55 | -15 |
| Pittsburgh Penguins | Pittsburgh Penguins | 21 | 6 | 13 | 19 | 0.90 | 2 | -4 |
| 51. | Evan Rodrigues (C/W) | Florida Panthers | 104 | 19 | 35 | 54 | 0.52 | 38 | 32 |
| 52. | Owen Tippett (RW/LW) | Philadelphia Flyers | 78 | 28 | 25 | 53 | 0.68 | 12 | -5 |
| 53. | Drew Doughty (D) | Los Angeles Kings | 87 | 17 | 36 | 53 | 0.61 | 58 | 11 |
| 54. | Evander Kane (LW/RW) | Edmonton Oilers | 97 | 28 | 24 | 52 | 0.54 | 122 | -11 |
| 55. | MacKenzie Weegar (D) | Calgary Flames | 82 | 20 | 32 | 52 | 0.63 | 51 | 2 |
| 56. | Chandler Stephenson (C/LW) | Vegas Golden Knights | 82 | 16 | 36 | 52 | 0.63 | 33 | -12 |
| 57. | Jonathan Huberdeau (LW/RW) | Calgary Flames | 81 | 12 | 40 | 52 | 0.64 | 49 | -29 |
| 58. | Jake DeBrusk (LW) | Boston Bruins | 93 | 24 | 27 | 51 | 0.55 | 20 | -1 |
| 59. | Thomas Harley (D) | Dallas Stars | 98 | 15 | 36 | 51 | 0.52 | 18 | 36 |
| 60. | Kris Letang (D) | Pittsburgh Penguins | 82 | 10 | 41 | 51 | 0.62 | 62 | 13 |
| 61. | Max Domi (C/W) | Toronto Maple Leafs | 87 | 10 | 41 | 51 | 0.59 | 124 | 11 |
| 62. | Warren Foegele (LW/C) | Edmonton Oilers | 104 | 23 | 26 | 49 | 0.47 | 72 | -4 |
| 63. | Nick Paul (LW/C) | Tampa Bay Lightning | 87 | 26 | 22 | 48 | 0.55 | 33 | -20 |
| 64. | Phillip Danault (C/LW) | Los Angeles Kings | 83 | 17 | 31 | 48 | 0.58 | 22 | 12 |
| 65. | Tyler Bertuzzi (LW/RW) | Toronto Maple Leafs | 87 | 22 | 25 | 47 | 0.54 | 59 | 4 |
| 66. | Anthony Cirelli (C) | Tampa Bay Lightning | 84 | 20 | 27 | 47 | 0.56 | 38 | -4 |
| 67. | Dylan Cozens (C/RW) | Buffalo Sabres | 79 | 18 | 29 | 47 | 0.59 | 42 | -4 |
| 68. | David Perron (LW/RW) | Detroit Red Wings | 76 | 17 | 30 | 47 | 0.62 | 55 | -12 |
| 69. | Brent Burns (D) | Carolina Hurricanes | 93 | 11 | 36 | 47 | 0.51 | 22 | 23 |
| 70. | Jeff Skinner (C/LW) | Buffalo Sabres | 74 | 24 | 22 | 46 | 0.62 | 34 | -2 |
| 71. | Brayden Schenn (C/W) | St. Louis Blues | 82 | 20 | 26 | 46 | 0.56 | 56 | -22 |
| 72. | Vince Dunn (D) | Seattle Kraken | 59 | 11 | 35 | 46 | 0.78 | 78 | 8 |
| 73. | Alexander Kerfoot (C/W) | Arizona Coyotes | 82 | 13 | 32 | 45 | 0.55 | 26 | -15 |
| 74. | Anthony Duclair (W/C) | totals | 78 | 24 | 20 | 44 | 0.56 | 34 | -11 |
| San Jose Sharks | San Jose Sharks | 56 | 16 | 11 | 27 | 0.48 | 28 | -12 |
| Tampa Bay Lightning | Tampa Bay Lightning | 22 | 8 | 9 | 17 | 0.77 | 6 | 1 |
| 75. | Anthony Mantha (RW/LW) | totals | 77 | 23 | 21 | 44 | 0.57 | 27 | 10 |
| Washington Capitals | Washington Capitals | 56 | 20 | 14 | 34 | 0.61 | 17 | 5 |
| Vegas Golden Knights | Vegas Golden Knights | 21 | 3 | 7 | 10 | 0.48 | 10 | 5 |
| 76. | Morgan Geekie (C/W) | Boston Bruins | 89 | 21 | 23 | 44 | 0.49 | 34 | 6 |
| 77. | Jordan Eberle (RW/C) | Seattle Kraken | 78 | 17 | 27 | 44 | 0.56 | 17 | 1 |
| 78. | Brandon Montour (D) | Florida Panthers | 90 | 11 | 33 | 44 | 0.49 | 58 | 1 |
| 79. | Travis Sanheim (D) | Philadelphia Flyers | 81 | 10 | 34 | 44 | 0.54 | 48 | -20 |
| 80. | Lawson Crouse (LW/RW) | Arizona Coyotes | 81 | 23 | 19 | 42 | 0.52 | 36 | -7 |
| 81. | Mason McTavish (C/LW) | Anaheim Ducks | 64 | 19 | 23 | 42 | 0.66 | 86 | -23 |
| 82. | Shea Theodore (D) | Vegas Golden Knights | 54 | 5 | 37 | 42 | 0.78 | 6 | 4 |
| 83. | Pierre-Luc Dubois (C/LW) | Los Angeles Kings | 87 | 17 | 24 | 41 | 0.47 | 90 | -9 |
| 84. | Jakob Chychrun (D) | Ottawa Senators | 82 | 14 | 27 | 41 | 0.50 | 60 | -30 |
| 85. | Morgan Frost (C/LW) | Philadelphia Flyers | 71 | 13 | 28 | 41 | 0.58 | 22 | 4 |
| 86. | Nicolas Roy (C/RW) | Vegas Golden Knights | 77 | 13 | 28 | 41 | 0.53 | 33 | 9 |
| 87. | Ryan Strome (C/RW) | Anaheim Ducks | 79 | 11 | 30 | 41 | 0.52 | 86 | -20 |
| 88. | Sean Durzi (D) | Arizona Coyotes | 76 | 9 | 32 | 41 | 0.54 | 63 | -1 |
| 89. | Gabriel Vilardi (C/RW) | Winnipeg Jets | 52 | 22 | 18 | 40 | 0.77 | 20 | 7 |
| 90. | Luke Evangelista (RW) | Nashville Predators | 86 | 17 | 23 | 40 | 0.47 | 20 | 0 |
| 91. | Andrew Mangiapane (W/C) | Calgary Flames | 75 | 14 | 26 | 40 | 0.53 | 47 | 7 |
| 92. | Reilly Smith (RW/LW) | Pittsburgh Penguins | 76 | 13 | 27 | 40 | 0.53 | 18 | 3 |
| 93. | Scott Laughton (C/LW) | Philadelphia Flyers | 82 | 13 | 26 | 39 | 0.48 | 69 | -9 |
| 94. | Jake Neighbours (LW/RW) | St. Louis Blues | 77 | 27 | 11 | 38 | 0.49 | 21 | -16 |
| 95. | Cole Perfetti (F) | Winnipeg Jets | 72 | 19 | 19 | 38 | 0.53 | 12 | 13 |
| 96. | Tom Wilson (RW) | Washington Capitals | 78 | 19 | 19 | 38 | 0.49 | 149 | -18 |
| 97. | Darnell Nurse (D) | Edmonton Oilers | 106 | 12 | 26 | 38 | 0.36 | 91 | -6 |
| 98. | Sean Couturier (C) | Philadelphia Flyers | 74 | 11 | 27 | 38 | 0.51 | 29 | -10 |
| 99. | Danton Heinen (LW/C) | Boston Bruins | 82 | 17 | 20 | 37 | 0.45 | 28 | 16 |
| 100. | Adam Lowry (C/LW) | Winnipeg Jets | 86 | 14 | 23 | 37 | 0.43 | 64 | 14 |