| 1. | Nathan MacKinnon (C/RW) | Colorado Avalanche | 82 | 51 | 89 | 140 | 1.71 | 42 | 35 |
| 2. | Connor McDavid (C) | Edmonton Oilers | 76 | 32 | 100 | 132 | 1.74 | 30 | 35 |
| 3. | Sam Reinhart (C/RW) | Florida Panthers | 82 | 57 | 37 | 94 | 1.15 | 31 | 29 |
| 4. | Sidney Crosby (C) | Pittsburgh Penguins | 82 | 42 | 52 | 94 | 1.15 | 40 | 7 |
| 5. | Brayden Point (C) | Tampa Bay Lightning | 81 | 46 | 44 | 90 | 1.11 | 14 | -16 |
| 6. | Cale Makar (D) | Colorado Avalanche | 77 | 21 | 69 | 90 | 1.17 | 16 | 15 |
| 7. | Robert Thomas (C/RW) | St. Louis Blues | 82 | 26 | 60 | 86 | 1.05 | 48 | 9 |
| 8. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 69 | 26 | 59 | 85 | 1.23 | 18 | 21 |
| 9. | Evan Bouchard (D) | Edmonton Oilers | 81 | 18 | 64 | 82 | 1.01 | 32 | 34 |
| 10. | Steven Stamkos (C/W) | Tampa Bay Lightning | 79 | 40 | 41 | 81 | 1.03 | 34 | -21 |
| 11. | Mathew Barzal (C/RW) | New York Islanders | 80 | 23 | 57 | 80 | 1.00 | 34 | -4 |
| 12. | Zach Hyman (W/C) | Edmonton Oilers | 80 | 54 | 23 | 77 | 0.96 | 48 | 36 |
| 13. | Nick Suzuki (C) | Montréal Canadiens | 82 | 33 | 44 | 77 | 0.94 | 36 | -14 |
| 14. | Nazem Kadri (C/LW) | Calgary Flames | 82 | 29 | 46 | 75 | 0.91 | 43 | 0 |
| 15. | Brandon Hagel (LW) | Tampa Bay Lightning | 82 | 26 | 49 | 75 | 0.91 | 79 | 1 |
| 16. | Carter Verhaeghe (C/LW) | Florida Panthers | 76 | 34 | 38 | 72 | 0.95 | 36 | 17 |
| 17. | Mark Scheifele (C) | Winnipeg Jets | 74 | 25 | 47 | 72 | 0.97 | 57 | 19 |
| 18. | Noah Dobson (D) | New York Islanders | 79 | 10 | 60 | 70 | 0.89 | 36 | 12 |
| 19. | Jonathan Marchessault (LW/RW) | Vegas Golden Knights | 82 | 42 | 27 | 69 | 0.84 | 40 | -2 |
| 20. | Ryan O'Reilly (C) | Nashville Predators | 82 | 26 | 43 | 69 | 0.84 | 18 | 6 |
| 21. | Josh Morrissey (D) | Winnipeg Jets | 81 | 10 | 59 | 69 | 0.85 | 44 | 34 |
| 22. | Travis Konecny (RW/LW) | Philadelphia Flyers | 76 | 33 | 35 | 68 | 0.89 | 67 | 4 |
| 23. | Bo Horvat (C) | New York Islanders | 81 | 33 | 35 | 68 | 0.84 | 39 | -1 |
| 24. | Seth Jarvis (C/W) | Carolina Hurricanes | 81 | 33 | 34 | 67 | 0.83 | 14 | 23 |
| 25. | Jordan Kyrou (C/RW) | St. Louis Blues | 82 | 31 | 36 | 67 | 0.82 | 22 | -12 |
| 26. | Brad Marchand (LW) | Boston Bruins | 82 | 29 | 38 | 67 | 0.82 | 78 | 2 |
| 27. | Dylan Strome (C) | Washington Capitals | 82 | 27 | 40 | 67 | 0.82 | 22 | -13 |
| 28. | Ryan Nugent-Hopkins (C/W) | Edmonton Oilers | 80 | 18 | 49 | 67 | 0.84 | 36 | 10 |
| 29. | Drake Batherson (RW/C) | Ottawa Senators | 82 | 28 | 38 | 66 | 0.80 | 42 | -9 |
| 30. | Wyatt Johnston (C/RW) | Dallas Stars | 82 | 32 | 33 | 65 | 0.79 | 38 | 14 |
| 31. | John Tavares (C/LW) | Toronto Maple Leafs | 80 | 29 | 36 | 65 | 0.81 | 30 | 2 |
| 32. | Matt Duchene (C/W) | Dallas Stars | 80 | 25 | 40 | 65 | 0.81 | 20 | 15 |
| 33. | Claude Giroux (W/C) | Ottawa Senators | 82 | 21 | 43 | 64 | 0.78 | 26 | -14 |
| 34. | Jared McCann (C/W) | Seattle Kraken | 80 | 29 | 33 | 62 | 0.78 | 31 | -10 |
| 35. | Mike Matheson (D) | Montréal Canadiens | 82 | 11 | 51 | 62 | 0.76 | 58 | -24 |
| 36. | Connor Bedard (C/LW) | Chicago Blackhawks | 68 | 22 | 39 | 61 | 0.90 | 28 | -44 |
| 37. | Jamie Benn (LW/C) | Dallas Stars | 82 | 21 | 39 | 60 | 0.73 | 41 | 8 |
| 38. | Sean Monahan (C/LW) | totals | 83 | 26 | 33 | 59 | 0.71 | 12 | -1 |
| Montréal Canadiens | Montréal Canadiens | 49 | 13 | 22 | 35 | 0.71 | 10 | -10 |
| Winnipeg Jets | Winnipeg Jets | 34 | 13 | 11 | 24 | 0.71 | 2 | 9 |
| 39. | Morgan Rielly (D) | Toronto Maple Leafs | 72 | 7 | 51 | 58 | 0.81 | 27 | 7 |
| 40. | Alexis Lafrenière (RW/LW) | New York Rangers | 82 | 28 | 29 | 57 | 0.70 | 40 | 2 |
| 41. | Jonathan Drouin (LW/C) | Colorado Avalanche | 79 | 19 | 37 | 56 | 0.71 | 28 | 12 |
| 42. | Tyler Toffoli (RW/C) | totals | 79 | 33 | 22 | 55 | 0.70 | 14 | -6 |
| New Jersey Devils | New Jersey Devils | 61 | 26 | 18 | 44 | 0.72 | 12 | -15 |
| Winnipeg Jets | Winnipeg Jets | 18 | 7 | 4 | 11 | 0.61 | 2 | 9 |
| 43. | Quinton Byfield (C/LW) | Los Angeles Kings | 80 | 20 | 35 | 55 | 0.69 | 42 | 19 |
| 44. | Michael Bunting (LW/RW) | totals | 81 | 19 | 36 | 55 | 0.68 | 57 | -19 |
| Carolina Hurricanes | Carolina Hurricanes | 60 | 13 | 23 | 36 | 0.60 | 55 | -15 |
| Pittsburgh Penguins | Pittsburgh Penguins | 21 | 6 | 13 | 19 | 0.90 | 2 | -4 |
| 45. | Owen Tippett (RW/LW) | Philadelphia Flyers | 78 | 28 | 25 | 53 | 0.68 | 12 | -5 |
| 46. | Mason Marchment (LW/C) | Dallas Stars | 81 | 22 | 31 | 53 | 0.65 | 54 | 22 |
| 47. | Mark Stone (RW) | Vegas Golden Knights | 56 | 16 | 37 | 53 | 0.95 | 22 | 1 |
| 48. | Tyler Seguin (C/RW) | Dallas Stars | 68 | 25 | 27 | 52 | 0.76 | 26 | 10 |
| 49. | MacKenzie Weegar (D) | Calgary Flames | 82 | 20 | 32 | 52 | 0.63 | 51 | 2 |
| 50. | Jonathan Huberdeau (LW/RW) | Calgary Flames | 81 | 12 | 40 | 52 | 0.64 | 49 | -29 |
| 51. | Adam Henrique (C/LW) | totals | 82 | 24 | 27 | 51 | 0.62 | 37 | 9 |
| Anaheim Ducks | Anaheim Ducks | 60 | 18 | 24 | 42 | 0.70 | 33 | 3 |
| Edmonton Oilers | Edmonton Oilers | 22 | 6 | 3 | 9 | 0.41 | 4 | 6 |
| 52. | Chandler Stephenson (C/LW) | Vegas Golden Knights | 75 | 16 | 35 | 51 | 0.68 | 25 | -9 |
| 53. | Kris Letang (D) | Pittsburgh Penguins | 82 | 10 | 41 | 51 | 0.62 | 62 | 13 |
| 54. | Drew Doughty (D) | Los Angeles Kings | 82 | 15 | 35 | 50 | 0.61 | 44 | 15 |
| 55. | Devon Toews (D) | Colorado Avalanche | 82 | 12 | 38 | 50 | 0.61 | 18 | 28 |
| 56. | Dylan Cozens (C/RW) | Buffalo Sabres | 79 | 18 | 29 | 47 | 0.59 | 42 | -4 |
| 57. | David Perron (LW/RW) | Detroit Red Wings | 76 | 17 | 30 | 47 | 0.62 | 55 | -12 |
| 58. | Phillip Danault (C/LW) | Los Angeles Kings | 78 | 17 | 30 | 47 | 0.60 | 18 | 12 |
| 59. | Thomas Harley (D) | Dallas Stars | 79 | 15 | 32 | 47 | 0.59 | 18 | 28 |
| 60. | Max Domi (C/W) | Toronto Maple Leafs | 80 | 9 | 38 | 47 | 0.59 | 118 | 10 |
| 61. | Jeff Skinner (C/LW) | Buffalo Sabres | 74 | 24 | 22 | 46 | 0.62 | 34 | -2 |
| 62. | Nick Paul (LW/C) | Tampa Bay Lightning | 82 | 24 | 22 | 46 | 0.56 | 27 | -16 |
| 63. | Brayden Schenn (C/W) | St. Louis Blues | 82 | 20 | 26 | 46 | 0.56 | 56 | -22 |
| 64. | Vince Dunn (D) | Seattle Kraken | 59 | 11 | 35 | 46 | 0.78 | 78 | 8 |
| 65. | Anthony Cirelli (C) | Tampa Bay Lightning | 79 | 20 | 25 | 45 | 0.57 | 38 | 2 |
| 66. | Alexander Kerfoot (C/W) | Arizona Coyotes | 82 | 13 | 32 | 45 | 0.55 | 26 | -15 |
| 67. | Evander Kane (LW/RW) | Edmonton Oilers | 77 | 24 | 20 | 44 | 0.57 | 85 | -4 |
| 68. | Anthony Mantha (RW/LW) | totals | 74 | 23 | 21 | 44 | 0.59 | 25 | 11 |
| Washington Capitals | Washington Capitals | 56 | 20 | 14 | 34 | 0.61 | 17 | 5 |
| Vegas Golden Knights | Vegas Golden Knights | 18 | 3 | 7 | 10 | 0.56 | 8 | 6 |
| 69. | Jordan Eberle (RW/C) | Seattle Kraken | 78 | 17 | 27 | 44 | 0.56 | 17 | 1 |
| 70. | Travis Sanheim (D) | Philadelphia Flyers | 81 | 10 | 34 | 44 | 0.54 | 48 | -20 |
| 71. | Tyler Bertuzzi (LW/RW) | Toronto Maple Leafs | 80 | 21 | 22 | 43 | 0.54 | 53 | 2 |
| 72. | Brent Burns (D) | Carolina Hurricanes | 82 | 10 | 33 | 43 | 0.52 | 20 | 19 |
| 73. | Anthony Duclair (W/C) | totals | 73 | 24 | 18 | 42 | 0.58 | 34 | -8 |
| San Jose Sharks | San Jose Sharks | 56 | 16 | 11 | 27 | 0.48 | 28 | -12 |
| Tampa Bay Lightning | Tampa Bay Lightning | 17 | 8 | 7 | 15 | 0.88 | 6 | 4 |
| 74. | Lawson Crouse (LW/RW) | Arizona Coyotes | 81 | 23 | 19 | 42 | 0.52 | 36 | -7 |
| 75. | Mason McTavish (C/LW) | Anaheim Ducks | 64 | 19 | 23 | 42 | 0.66 | 86 | -23 |
| 76. | Shea Theodore (D) | Vegas Golden Knights | 47 | 5 | 37 | 42 | 0.89 | 6 | 4 |
| 77. | Sam Bennett (C/LW) | Florida Panthers | 69 | 20 | 21 | 41 | 0.59 | 100 | 17 |
| 78. | Warren Foegele (LW/C) | Edmonton Oilers | 82 | 20 | 21 | 41 | 0.50 | 47 | 3 |
| 79. | Jakob Chychrun (D) | Ottawa Senators | 82 | 14 | 27 | 41 | 0.50 | 60 | -30 |
| 80. | Nicolas Roy (C/RW) | Vegas Golden Knights | 70 | 13 | 28 | 41 | 0.59 | 29 | 8 |
| 81. | Morgan Frost (C/LW) | Philadelphia Flyers | 71 | 13 | 28 | 41 | 0.58 | 22 | 4 |
| 82. | Ryan Strome (C/RW) | Anaheim Ducks | 79 | 11 | 30 | 41 | 0.52 | 86 | -20 |
| 83. | Sean Durzi (D) | Arizona Coyotes | 76 | 9 | 32 | 41 | 0.54 | 63 | -1 |
| 84. | Jake DeBrusk (LW) | Boston Bruins | 80 | 19 | 21 | 40 | 0.50 | 18 | 4 |
| 85. | Pierre-Luc Dubois (C/LW) | Los Angeles Kings | 82 | 16 | 24 | 40 | 0.49 | 70 | -9 |
| 86. | Andrew Mangiapane (W/C) | Calgary Flames | 75 | 14 | 26 | 40 | 0.53 | 47 | 7 |
| 87. | Reilly Smith (RW/LW) | Pittsburgh Penguins | 76 | 13 | 27 | 40 | 0.53 | 18 | 3 |
| 88. | Morgan Geekie (C/W) | Boston Bruins | 76 | 17 | 22 | 39 | 0.51 | 28 | 6 |
| 89. | Luke Evangelista (RW) | Nashville Predators | 80 | 16 | 23 | 39 | 0.49 | 18 | 0 |
| 90. | Scott Laughton (C/LW) | Philadelphia Flyers | 82 | 13 | 26 | 39 | 0.48 | 69 | -9 |
| 91. | Evan Rodrigues (C/W) | Florida Panthers | 80 | 12 | 27 | 39 | 0.49 | 34 | 26 |
| 92. | Jake Neighbours (LW/RW) | St. Louis Blues | 77 | 27 | 11 | 38 | 0.49 | 21 | -16 |
| 93. | Cole Perfetti (F) | Winnipeg Jets | 71 | 19 | 19 | 38 | 0.54 | 12 | 13 |
| 94. | Sean Couturier (C) | Philadelphia Flyers | 74 | 11 | 27 | 38 | 0.51 | 29 | -10 |
| 95. | Gabriel Vilardi (C/RW) | Winnipeg Jets | 47 | 22 | 14 | 36 | 0.77 | 14 | 11 |
| 96. | Alex Killorn (LW/RW) | Anaheim Ducks | 63 | 18 | 18 | 36 | 0.57 | 54 | -15 |
| 97. | Danton Heinen (LW/C) | Boston Bruins | 74 | 17 | 19 | 36 | 0.49 | 28 | 16 |
| 98. | Boone Jenner (C/LW) | Columbus Blue Jackets | 58 | 22 | 13 | 35 | 0.60 | 28 | -8 |
| 99. | Jason Dickinson (C/LW) | Chicago Blackhawks | 82 | 22 | 13 | 35 | 0.43 | 43 | 4 |
| 100. | Dylan Guenther (RW/LW) | Arizona Coyotes | 45 | 18 | 17 | 35 | 0.78 | 14 | -1 |