| 1. | Nathan MacKinnon (C/RW) | Colorado Avalanche | 79 | 32 | 84 | 116 | 1.47 | 41 | 25 |
| 2. | Mitchell Marner (RW/C) | Toronto Maple Leafs | 81 | 27 | 75 | 102 | 1.26 | 14 | 18 |
| 3. | Connor McDavid (C) | Edmonton Oilers | 67 | 26 | 74 | 100 | 1.49 | 37 | 20 |
| 4. | Cale Makar (D) | Colorado Avalanche | 80 | 30 | 62 | 92 | 1.15 | 14 | 28 |
| 5. | Sidney Crosby (C) | Pittsburgh Penguins | 80 | 33 | 58 | 91 | 1.14 | 31 | -20 |
| 6. | Brandon Hagel (LW) | Tampa Bay Lightning | 82 | 35 | 55 | 90 | 1.10 | 58 | 33 |
| 7. | Nick Suzuki (C) | Montréal Canadiens | 82 | 30 | 59 | 89 | 1.09 | 8 | 19 |
| 8. | Mark Scheifele (C) | Winnipeg Jets | 82 | 39 | 48 | 87 | 1.06 | 61 | 12 |
| 9. | Brayden Point (C) | Tampa Bay Lightning | 77 | 42 | 40 | 82 | 1.06 | 7 | 17 |
| 10. | Matt Duchene (C/W) | Dallas Stars | 82 | 30 | 52 | 82 | 1.00 | 12 | 13 |
| 11. | Dylan Strome (C) | Washington Capitals | 82 | 29 | 53 | 82 | 1.00 | 34 | 2 |
| 12. | Sam Reinhart (C/RW) | Florida Panthers | 79 | 39 | 42 | 81 | 1.03 | 27 | 6 |
| 13. | Robert Thomas (C/RW) | St. Louis Blues | 70 | 21 | 60 | 81 | 1.16 | 20 | 20 |
| 14. | Travis Konecny (RW/LW) | Philadelphia Flyers | 82 | 24 | 52 | 76 | 0.93 | 53 | -17 |
| 15. | John Tavares (C/LW) | Toronto Maple Leafs | 75 | 38 | 36 | 74 | 0.99 | 46 | 10 |
| 16. | Wyatt Johnston (C/RW) | Dallas Stars | 82 | 33 | 38 | 71 | 0.87 | 14 | 2 |
| 17. | Jordan Kyrou (C/RW) | St. Louis Blues | 82 | 36 | 34 | 70 | 0.85 | 20 | 23 |
| 18. | Drake Batherson (RW/C) | Ottawa Senators | 82 | 26 | 42 | 68 | 0.83 | 30 | -9 |
| 19. | Nazem Kadri (C/LW) | Calgary Flames | 82 | 35 | 32 | 67 | 0.82 | 72 | -17 |
| 20. | Seth Jarvis (C/W) | Carolina Hurricanes | 73 | 32 | 35 | 67 | 0.92 | 16 | 12 |
| 21. | Connor Bedard (C/LW) | Chicago Blackhawks | 82 | 23 | 44 | 67 | 0.82 | 70 | -36 |
| 22. | Mark Stone (RW) | Vegas Golden Knights | 66 | 19 | 48 | 67 | 1.02 | 14 | 22 |
| 23. | Evan Bouchard (D) | Edmonton Oilers | 82 | 14 | 53 | 67 | 0.82 | 32 | 14 |
| 24. | Pierre-Luc Dubois (C/LW) | Washington Capitals | 82 | 20 | 46 | 66 | 0.80 | 76 | 27 |
| 25. | Tom Wilson (RW) | Washington Capitals | 81 | 33 | 32 | 65 | 0.80 | 100 | 20 |
| 26. | Dylan Holloway (W/C) | St. Louis Blues | 77 | 26 | 37 | 63 | 0.82 | 10 | 21 |
| 27. | Macklin Celebrini (C/LW) | San Jose Sharks | 70 | 25 | 38 | 63 | 0.90 | 28 | -31 |
| 28. | Jonathan Huberdeau (LW/RW) | Calgary Flames | 81 | 28 | 34 | 62 | 0.77 | 34 | -13 |
| 29. | Josh Morrissey (D) | Winnipeg Jets | 80 | 14 | 48 | 62 | 0.78 | 22 | 17 |
| 30. | Gabriel Vilardi (C/RW) | Winnipeg Jets | 71 | 27 | 34 | 61 | 0.86 | 14 | 9 |
| 31. | Jared McCann (C/W) | Seattle Kraken | 82 | 22 | 39 | 61 | 0.74 | 18 | 8 |
| 32. | Dylan Guenther (RW/LW) | Utah Mammoth | 70 | 27 | 33 | 60 | 0.86 | 26 | -4 |
| 33. | Anthony Cirelli (C) | Tampa Bay Lightning | 80 | 27 | 32 | 59 | 0.74 | 28 | 30 |
| 34. | Morgan Geekie (C/W) | Boston Bruins | 77 | 33 | 24 | 57 | 0.74 | 22 | 3 |
| 35. | Bo Horvat (C) | New York Islanders | 81 | 28 | 29 | 57 | 0.70 | 16 | -4 |
| 36. | Connor McMichael (C/W) | Washington Capitals | 82 | 26 | 31 | 57 | 0.70 | 49 | 19 |
| 37. | Kent Johnson (C/W) | Columbus Blue Jackets | 68 | 24 | 33 | 57 | 0.84 | 16 | 2 |
| 38. | Sean Monahan (C/LW) | Columbus Blue Jackets | 54 | 19 | 38 | 57 | 1.06 | 20 | 19 |
| 39. | Shea Theodore (D) | Vegas Golden Knights | 67 | 7 | 50 | 57 | 0.85 | 26 | 18 |
| 40. | Jonathan Marchessault (LW/RW) | Nashville Predators | 78 | 21 | 35 | 56 | 0.72 | 37 | -29 |
| 41. | Adam Fantilli (C/LW) | Columbus Blue Jackets | 82 | 31 | 23 | 54 | 0.66 | 18 | 4 |
| 42. | Tyler Toffoli (RW/C) | San Jose Sharks | 78 | 30 | 24 | 54 | 0.69 | 14 | -21 |
| 43. | Quinton Byfield (C/LW) | Los Angeles Kings | 81 | 23 | 31 | 54 | 0.67 | 46 | 16 |
| 44. | Steven Stamkos (C/W) | Nashville Predators | 82 | 27 | 26 | 53 | 0.65 | 48 | -36 |
| 45. | Ryan O'Reilly (C) | Nashville Predators | 79 | 21 | 32 | 53 | 0.67 | 24 | -23 |
| 46. | Ryan McLeod (C/LW) | Buffalo Sabres | 79 | 20 | 33 | 53 | 0.67 | 16 | 13 |
| 47. | Carter Verhaeghe (C/LW) | Florida Panthers | 81 | 20 | 33 | 53 | 0.65 | 46 | -14 |
| 48. | Mason McTavish (C/LW) | Anaheim Ducks | 76 | 22 | 30 | 52 | 0.68 | 38 | 0 |
| 49. | Sam Bennett (C/LW) | Florida Panthers | 76 | 25 | 26 | 51 | 0.67 | 90 | -15 |
| 50. | Brad Marchand (LW) | totals | 71 | 23 | 28 | 51 | 0.72 | 64 | -7 |
| Boston Bruins | Boston Bruins | 61 | 21 | 26 | 47 | 0.77 | 62 | -8 |
| Florida Panthers | Florida Panthers | 10 | 2 | 2 | 4 | 0.40 | 2 | 1 |
| 51. | Chandler Stephenson (C/LW) | Seattle Kraken | 78 | 13 | 38 | 51 | 0.65 | 24 | -9 |
| 52. | Cole Perfetti (F) | Winnipeg Jets | 82 | 18 | 32 | 50 | 0.61 | 20 | 14 |
| 53. | Brayden Schenn (C/W) | St. Louis Blues | 82 | 18 | 32 | 50 | 0.61 | 61 | 3 |
| 54. | Thomas Harley (D) | Dallas Stars | 78 | 16 | 34 | 50 | 0.64 | 16 | 32 |
| 55. | Claude Giroux (W/C) | Ottawa Senators | 81 | 15 | 35 | 50 | 0.62 | 18 | -8 |
| 56. | Jaden Schwartz (LW) | Seattle Kraken | 81 | 26 | 23 | 49 | 0.60 | 24 | -6 |
| 57. | Ryan Nugent-Hopkins (C/W) | Edmonton Oilers | 78 | 20 | 29 | 49 | 0.63 | 24 | 4 |
| 58. | Jamie Benn (LW/C) | Dallas Stars | 80 | 16 | 33 | 49 | 0.61 | 70 | 3 |
| 59. | Jake DeBrusk (LW) | Vancouver Canucks | 82 | 28 | 20 | 48 | 0.59 | 18 | -15 |
| 60. | Mason Marchment (LW/C) | Dallas Stars | 62 | 22 | 25 | 47 | 0.76 | 53 | 15 |
| 61. | Jakob Chychrun (D) | Washington Capitals | 74 | 20 | 27 | 47 | 0.64 | 52 | 17 |
| 62. | Dylan Cozens (C/RW) | totals | 82 | 16 | 31 | 47 | 0.57 | 68 | -17 |
| Buffalo Sabres | Buffalo Sabres | 61 | 11 | 20 | 31 | 0.51 | 62 | -13 |
| Ottawa Senators | Ottawa Senators | 21 | 5 | 11 | 16 | 0.76 | 6 | -4 |
| 63. | MacKenzie Weegar (D) | Calgary Flames | 81 | 8 | 39 | 47 | 0.58 | 33 | 18 |
| 64. | Warren Foegele (LW/C) | Los Angeles Kings | 82 | 24 | 22 | 46 | 0.56 | 24 | 36 |
| 65. | Tyler Bertuzzi (LW/RW) | Chicago Blackhawks | 82 | 23 | 23 | 46 | 0.56 | 51 | -39 |
| 66. | Jake Neighbours (LW/RW) | St. Louis Blues | 82 | 22 | 24 | 46 | 0.56 | 56 | 0 |
| 67. | Barrett Hayton (C/LW) | Utah Mammoth | 82 | 20 | 26 | 46 | 0.56 | 45 | -6 |
| 68. | Will Cuylle (LW/RW) | New York Rangers | 82 | 20 | 25 | 45 | 0.55 | 42 | 12 |
| 69. | Alexis Lafrenière (RW/LW) | New York Rangers | 82 | 17 | 28 | 45 | 0.55 | 38 | -13 |
| 70. | Sean Couturier (C) | Philadelphia Flyers | 79 | 15 | 30 | 45 | 0.57 | 41 | 1 |
| 71. | Thomas Chabot (D) | Ottawa Senators | 80 | 9 | 36 | 45 | 0.56 | 24 | 17 |
| 72. | Zach Hyman (W/C) | Edmonton Oilers | 73 | 27 | 17 | 44 | 0.60 | 32 | 9 |
| 73. | Shane Wright (C) | Seattle Kraken | 79 | 19 | 25 | 44 | 0.56 | 18 | 4 |
| 74. | Devon Toews (D) | Colorado Avalanche | 76 | 10 | 34 | 44 | 0.58 | 26 | 30 |
| 75. | Tyson Foerster (RW) | Philadelphia Flyers | 81 | 25 | 18 | 43 | 0.53 | 49 | -9 |
| 76. | Owen Tippett (RW/LW) | Philadelphia Flyers | 77 | 20 | 23 | 43 | 0.56 | 16 | -12 |
| 77. | Phillip Danault (C/LW) | Los Angeles Kings | 80 | 8 | 35 | 43 | 0.54 | 26 | 20 |
| 78. | Taylor Hall (LW/C) | totals | 77 | 18 | 24 | 42 | 0.55 | 36 | -14 |
| Chicago Blackhawks | Chicago Blackhawks | 46 | 9 | 15 | 24 | 0.52 | 16 | -15 |
| Carolina Hurricanes | Carolina Hurricanes | 31 | 9 | 9 | 18 | 0.58 | 20 | 1 |
| 79. | Jean-Gabriel Pageau (C) | New York Islanders | 79 | 14 | 28 | 42 | 0.53 | 23 | 4 |
| 80. | Nick Paul (LW/C) | Tampa Bay Lightning | 76 | 22 | 19 | 41 | 0.54 | 30 | 13 |
| 81. | Brandon Montour (D) | Seattle Kraken | 81 | 18 | 23 | 41 | 0.51 | 70 | -22 |
| 82. | Ryan Strome (C/RW) | Anaheim Ducks | 82 | 10 | 31 | 41 | 0.50 | 70 | -3 |
| 83. | Morgan Rielly (D) | Toronto Maple Leafs | 82 | 7 | 34 | 41 | 0.50 | 21 | -8 |
| 84. | Brett Howden (C/LW) | Vegas Golden Knights | 80 | 23 | 17 | 40 | 0.50 | 46 | 17 |
| 85. | Reilly Smith (RW/LW) | totals | 79 | 13 | 27 | 40 | 0.51 | 24 | 10 |
| New York Rangers | New York Rangers | 58 | 10 | 19 | 29 | 0.50 | 22 | -1 |
| Vegas Golden Knights | Vegas Golden Knights | 21 | 3 | 8 | 11 | 0.52 | 2 | 11 |
| 86. | Dougie Hamilton (D) | New Jersey Devils | 64 | 9 | 31 | 40 | 0.63 | 30 | 8 |
| 87. | Jake Walman (D) | totals | 65 | 7 | 33 | 40 | 0.62 | 42 | 4 |
| San Jose Sharks | San Jose Sharks | 50 | 6 | 26 | 32 | 0.64 | 36 | -1 |
| Edmonton Oilers | Edmonton Oilers | 15 | 1 | 7 | 8 | 0.53 | 6 | 5 |
| 88. | Owen Power (D) | Buffalo Sabres | 79 | 7 | 33 | 40 | 0.51 | 16 | -13 |
| 89. | Jack Quinn (RW/LW) | Buffalo Sabres | 74 | 15 | 24 | 39 | 0.53 | 18 | -18 |
| 90. | Vince Dunn (D) | Seattle Kraken | 62 | 11 | 28 | 39 | 0.63 | 33 | -3 |
| 91. | Noah Dobson (D) | New York Islanders | 71 | 10 | 29 | 39 | 0.55 | 28 | -16 |
| 92. | Brendan Gallagher (RW) | Montréal Canadiens | 82 | 21 | 17 | 38 | 0.46 | 39 | -6 |
| 93. | Michael Bunting (LW/RW) | totals | 76 | 19 | 19 | 38 | 0.50 | 68 | -19 |
| Pittsburgh Penguins | Pittsburgh Penguins | 58 | 14 | 15 | 29 | 0.50 | 48 | -18 |
| Nashville Predators | Nashville Predators | 18 | 5 | 4 | 9 | 0.50 | 20 | -1 |
| 94. | Logan Stankoven (C/RW) | totals | 78 | 14 | 24 | 38 | 0.49 | 18 | -1 |
| Dallas Stars | Dallas Stars | 59 | 9 | 20 | 29 | 0.49 | 6 | 2 |
| Carolina Hurricanes | Carolina Hurricanes | 19 | 5 | 4 | 9 | 0.47 | 12 | -3 |
| 95. | Bowen Byram (D) | Buffalo Sabres | 82 | 7 | 31 | 38 | 0.46 | 46 | 11 |
| 96. | Alex Killorn (LW/RW) | Anaheim Ducks | 82 | 19 | 18 | 37 | 0.45 | 30 | 12 |
| 97. | Frédérick Gaudreau (C/RW) | Minnesota Wild | 82 | 18 | 19 | 37 | 0.45 | 8 | -2 |
| 98. | Morgan Frost (C/LW) | totals | 81 | 14 | 23 | 37 | 0.46 | 22 | -17 |
| Philadelphia Flyers | Philadelphia Flyers | 49 | 11 | 14 | 25 | 0.51 | 16 | -11 |
| Calgary Flames | Calgary Flames | 32 | 3 | 9 | 12 | 0.38 | 6 | -6 |
| 99. | Jonathan Drouin (LW/C) | Colorado Avalanche | 43 | 11 | 26 | 37 | 0.86 | 6 | 4 |
| 100. | Darren Raddysh (D) | Tampa Bay Lightning | 73 | 6 | 31 | 37 | 0.51 | 14 | 9 |